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to explore the impact of preoperative neoadjuvant immunotherapy on perioperative outcomes and long-term prognosis of locally advanced NSCLC in the real world
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| chemoimmunotherapy group 1 | patients received different cycles of neoadjuvant chemoimmunotherapy |
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| chemoimmunotherapy group 2 | the duration of before patients received surgery after neoadjuvant chemoimmunotherapy |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cycles of neoadjuvant therapy and duration of waiting for surgery | Other | We intended to explore the cycles of neoadjuvant therapy and duration of waiting for surgery on the perioperative outcomes and long-term prognosis of locally advanced NSCLC in the real world |
| Measure | Description | Time Frame |
|---|---|---|
| major pathological remission | proportion of patients with no more than 10% residual viable tumor cells; patients who showed no viable tumor in the lung primary setting but lymph nodes show viable metastatic carcinoma were also classified as MPR | one month |
| pathological complete remission | proportion of patients without residual viable tumor cell on evaluation of resected lung cancer specimens including all sampled regional lymph nodes | one month |
| survival time | time since diagnosed with NSCLC | 5 years |
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Inclusion Criteria:
Confirmed as primary lung cancer through cytology or histological examination;
ECOG score of 0 or 1; â‘¢ 18 years old or above;
Received imaging examination, with a preliminary clinical staging of stage III;
Exclusion Criteria:
Patients with combined small cell lung cancer; â‘¡ Patients with severe liver/kidney dysfunction, cardiovascular disease, or systemic immune disorders;
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locally advanced NSCLC meeting the above crateria
The datasets are available upon reasonable request.
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| ID | Term |
|---|---|
| D002289 | Carcinoma, Non-Small-Cell Lung |
| ID | Term |
|---|---|
| D002283 | Carcinoma, Bronchogenic |
| D001984 | Bronchial Neoplasms |
| D008175 | Lung Neoplasms |
| D012142 | Respiratory Tract Neoplasms |
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| ID | Term |
|---|---|
| D013514 | Surgical Procedures, Operative |
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| D013899 |
| Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |