Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Large renal pelvic stones are frequently managed with percutaneous nephrolithotomy (PCNL) but laparoscopic pyelolithotomy (LPL) can be an alternative procedure when performed by skilled surgeons to achieve excellent outcomes in terms of stone free status, operative time, postoperative kidney function, hospitalization duration, and complications.
there are two methods for LPL surgery : Transperitoneal (TLP) and Retroperitoneal (RLP).
RLP associated with shorter mean time for oral intake, and mean hospital stay after surgery.
The surgical exposure in the transperitoneal route for LP is familiar to the majority of surgeons. Also, a much larger working space is available and there are various established anatomical landmarks for performing the surgery effectively. This study introduces a modified technique that creates application of posterior pyelotomy in TLP to achieve the advantages of RLP
This is a randomized controlled clinical trial that aims to collect a sample within two years from the date of approval of the Scientific Research Council at Damascus University.
The study will focus on a group of patients who will undergo a transperitoneal laparoscopic pyelolithotomy surgery.
The patients will be randomly divided into two groups. The first group will undergo a traditional transperitoneal laparoscopic pyelolithotomy, which involves application of anterior pyelotomy.
The second group will receive a modified transperitoneal laparoscopic pyelolithotomy, which involves application of posterior pyelotomy.
The data will be compared between the two groups in terms of the mean duration of surgery ,mean time for oral intake ,and mean hospital stay
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anterior Pyelotomy | Experimental | Traditional transperitoneal laparoscopic pyelolithotomy: Patients who were randomized to receive classic transperitoneal laparoscopic pyelolithotomy |
|
| Posterior Pyelotomy | Experimental | Modified transperitoneal laparoscopic pyelolithotomy: Patients who were randomized to receive modified transperitoneal laparoscopic pyelolithotomy by applying posterior pyelotomy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| traditional transperitoneal laparoscopic pyelolithotomy | Procedure | Performing anterior Pyelotomy. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Operative time | the duration of the surgical procedure. It is measured by minutes, and calculated from establishing the pneumoperitoneum until the surgery is completed by suturing the skin. It will be measured in the outcome by the mean | at the end of surgery in the operating room |
| Days for oral intake | the number of days to start introducing oral fluids and food after surgery with good acceptance, and without vomiting or flatulence. It will be measured in the outcome by the mean | Up to one week after surgery |
| Days of hospital stay | the number of days the patient stayed in the hospital after surgery. It will be measured in the outcome by the mean | up to ten days after surgery |
| Postoperative urine leak | considered to be present when the drain contained >30 cc of urine the morning after surgery. It is measured by answering the question: Is there any urinary leakage, yes or no? It will be measured in the outcome by the ratio | up to three days after surgery |
| stone-free status | postoperative radiological imaging demonstrating evidence of residual stones It will be measured in the Outcome by the ratio | Up to one week after surgery |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Damascus University | Damascus | Syria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34927230 | Background | Soltani MH, Hossein Kashi A, Farshid S, Mantegy SJ, Valizadeh R. Transperitoneal Laparoscopic Pyelolithotomy versus Percutaneous Nephrolithotomy for Treating the Patients with Staghorn Kidney Stones: A Randomized Clinical Trial. Urol J. 2021 Dec 20;19(1):28-33. doi: 10.22037/uj.v18i.6831. | |
| 28859655 | Background |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| modified transperitoneal laparoscopic pyelolithotomy | Procedure | Performing posterior pyelotomy |
|
| Bai Y, Tang Y, Deng L, Wang X, Yang Y, Wang J, Han P. Management of large renal stones: laparoscopic pyelolithotomy versus percutaneous nephrolithotomy. BMC Urol. 2017 Aug 31;17(1):75. doi: 10.1186/s12894-017-0266-7. |
| 19183229 | Background | Al-Hunayan A, Abdulhalim H, El-Bakry E, Hassabo M, Kehinde EO. Laparoscopic pyelolithotomy: is the retroperitoneal route a better approach? Int J Urol. 2009 Feb;16(2):181-6. doi: 10.1111/j.1442-2042.2008.02210.x. Epub 2008 Dec 2. |
| 8126827 | Background | Gaur DD, Agarwal DK, Purohit KC, Darshane AS. Retroperitoneal laparoscopic pyelolithotomy. J Urol. 1994 Apr;151(4):927-9. doi: 10.1016/s0022-5347(17)35124-8. |
| 31868562 | Background | Radfar MH, Dadpour M, Simforoosh N, Basiri A, Nouralizadeh A, Shakiba B, Valipour R, Zare A. Laparoscopic pyelolithotomy in patients with previous ipsilateral renal stone surgery. Urologia. 2021 Feb;88(1):41-45. doi: 10.1177/0391560319890993. Epub 2019 Dec 23. |
| 23454154 | Background | Wang X, Li S, Liu T, Guo Y, Yang Z. Laparoscopic pyelolithotomy compared to percutaneous nephrolithotomy as surgical management for large renal pelvic calculi: a meta-analysis. J Urol. 2013 Sep;190(3):888-93. doi: 10.1016/j.juro.2013.02.092. Epub 2013 Feb 27. |
| ID | Term |
|---|---|
| D007669 | Kidney Calculi |
| ID | Term |
|---|---|
| D053040 | Nephrolithiasis |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D014545 | Urinary Calculi |
| D052801 | Male Urogenital Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
Not provided
Not provided