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This study aims to assess Effectiveness of Pre-administered Natural Sweet-tasting Solution (honey) for Decreasing Pain Associated with Dental Injections (infiltration) prior to dental extraction in 6-8 years old healthy Children (first dental visit) In comparison to topical anesthesia.
The administration of local anesthetics is one of the most dreaded or anxiety-inducing triggers in a dental setup. Patients, particularly children, may be fearful of dental injections, which may prevent them from seeking dental treatment. Even though profound local anesthesia aids in the treatment of pediatric patients in terms of reducing their anxiety and pain during restorative and surgical procedures, the fear of needles has been cited as a barrier to develop proper dental care. Numerous techniques have been researched in an attempt to minimize the pain and distress associated with these dental injections, varying from localized methods to distraction techniques. The localized methods include application of topical agents, altering the rate of injection, increasing the pH of local anesthetics by buffering and pretreatment with lasers. Instruments such as CCLA System (computer-controlled local anesthetic delivery system) and dental vibe are also available to make dental injections more comfortable. Studies have found that sweet flavored solutions, mainly 30% sucrose, given orally prior to cutaneous procedures can reduce discomfort in neonates undergoing heel sticks and venipuncture. Effectiveness of sucrose in the treatment of, procedural pain in newborns and babies has been verified in a Cochrane reviews.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Effect of Pre-administered honey for Decreasing Pain of Dental Injections | Experimental | The participants were asked to drink 5 mL of honey solution before injecting on the experimental side, the patient was asked to hold the solution in the mouth for a minute and then to spit it out . |
|
| topical anesthesia | Other | benzocaine 20% gel was applied to the test sites on side of the jaw with a cotton tip applicator which was completely soaked for a period of 5 minutes. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| honey | Dietary Supplement | analgesic effect of honey |
|
| Measure | Description | Time Frame |
|---|---|---|
| Pain perception during Dental injection Dental injection Pain perception during Dental injection | Wong-Baker ratting scale 0 happy ,2 hurts a little bit,4 "hurts a little more"6 hurts even more,8 hurts a whole lot"10hurts worst" Rating scale Wong-Baker Rating scale | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Child behavior during dental injection | The SEM(sound, eye, motor) scale Scale from (0-4) | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| heart rate during dental injection | Pulse oximeter | through study completion, an average of 1 year". |
Inclusion Criteria:
Exclusion Criteria
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alaa Ahmed Mohamed, B.D. | Contact | 01126160975 | alaasalah199623@gmail.com | |
| Soad abdelmoniem, Professor | Contact | 01005654355 | soad.abdelmoniem@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Nourhan Omar Elgebaly, Lecturer | Outpatient clinic, department of Pediatric Dentistry, Faculty of Dentistry, Cairo University. | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35656683 | Background | Janiani P, Gurunathan D. Effectiveness of Pre-administered Natural Sweet-tasting Solution for Decreasing Pain Associated with Dental Injections in Children: A Split-mouth Randomized Controlled Trial. J Contemp Dent Pract. 2021 Dec 1;22(12):1434-1437. | |
| 31650314 | Background | Gumus H, Aydinbelge M. Evaluation of effect of warm local anesthetics on pain perception during dental injections in children: a split-mouth randomized clinical trial. Clin Oral Investig. 2020 Jul;24(7):2315-2319. doi: 10.1007/s00784-019-03086-6. Epub 2019 Oct 24. |
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| ID | Term |
|---|---|
| D000377 | Agnosia |
| D010146 | Pain |
| ID | Term |
|---|---|
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D006722 | Honey |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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This trial is a randomized clinical trial (parallel design 1:1).
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This research will be a double blinded study, where the patient (participant) and the statistician will be blind to the treatment groups.
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |