Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to pilot and refine an online behavioral intervention based on Positive Affect Training (PAT) that aims to increase positive emotional attitudes and decrease negative emotional attitudes toward endocrine therapy (ET, i.e., anti-hormonal medication) and to increase positive affect and decrease negative affect more generally, among post-treatment breast cancer survivors who are prescribed ET to prevent recurrence of breast cancer.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Online Program | Experimental | Online program |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| THRIVE Online PAT Program | Behavioral | Online program: behavioral intervention based on Positive Affect Training (PAT) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Acceptability of THRIVE intervention (AIM) | Acceptability of Implementation Measure (Weimer et al., 2017) | 1 week post-intervention |
| Feasibility of THRIVE intervention | Feasibility of Intervention Measure (Weimer et al., 2017) | 1 week post-intervention |
| Client Satisfaction Survey | Satisfaction and feedback on THRIVE intervention | 1 week post-intervention |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Adjuvant endocrine therapy medication adherence (patient-reported) | Wilson et al, 2016, validated 3-item measure of adherence to oral medication | change from baseline (pre) to 1 week post-intervention (post) |
| Positive and Negative Affect Scales (PANAS) |
Inclusion Criteria:
hormone receptor-positive breast cancer stages 0-3
have finished primary treatment (chemotherapy/radiation/surgery)
are prescribed endocrine therapy (ET) currently or within the last two years
score above specified cut off (range, 0-10) on any of three questions:
have internet access to complete online assessments and intervention components or agree to use and return a study wifi-activated iPad.
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Joanna Arch, PhD | University of Colorado, Boulder | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Colorado Boulder | Boulder | Colorado | 80309 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30998048 | Background | Craske MG, Meuret AE, Ritz T, Treanor M, Dour H, Rosenfield D. Positive affect treatment for depression and anxiety: A randomized clinical trial for a core feature of anhedonia. J Consult Clin Psychol. 2019 May;87(5):457-471. doi: 10.1037/ccp0000396. | |
| 27699943 | Background | Craske MG, Meuret AE, Ritz T, Treanor M, Dour HJ. Treatment for Anhedonia: A Neuroscience Driven Approach. Depress Anxiety. 2016 Oct;33(10):927-938. doi: 10.1002/da.22490. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| D002285 | Carcinoma, Intraductal, Noninfiltrating |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Scales that assess positive and negative affect, respectively
| change from baseline (pre) to 1 week post-intervention (post) |
| Emotional attitudes toward adjuvant endocrine therapy | assessed each positive and negative affective attitudes toward (e.g., emotions associated with) adjuvant endocrine therapy on separate scales, from Rosenberg et al, 2015 | change from baseline (pre) to 1 week post-intervention (post) |
| Patient Health Questionnaire-8 | Depression questionnaire | change from baseline (pre) to 1 week post-intervention (post) |
| Generalized Anxiety Disorder-7 | anxiety symptom questionnaire | change from baseline (pre) to 1 week post-intervention (post) |
| 36892884 | Background | Craske MG, Meuret AE, Echiverri-Cohen A, Rosenfield D, Ritz T. Positive affect treatment targets reward sensitivity: A randomized controlled trial. J Consult Clin Psychol. 2023 Jun;91(6):350-366. doi: 10.1037/ccp0000805. Epub 2023 Mar 9. |
| 35323853 | Background | Arch JJ, Crespi CM, Levin ME, Genung SR, Nealis M, Mitchell JL, Bright EE, Albright K, Magidson JF, Stanton AL. Randomized Controlled Pilot Trial of a Low-Touch Remotely-Delivered Values Intervention to Promote Adherence to Adjuvant Endocrine Therapy Among Breast Cancer Survivors. Ann Behav Med. 2022 Aug 2;56(8):856-871. doi: 10.1093/abm/kaab118. |
| D017437 |
| Skin and Connective Tissue Diseases |
| D000230 | Adenocarcinoma |
| D002277 | Carcinoma |
| D009375 | Neoplasms, Glandular and Epithelial |
| D009370 | Neoplasms by Histologic Type |
| D000071960 | Breast Carcinoma In Situ |
| D002278 | Carcinoma in Situ |
| D018299 | Neoplasms, Ductal, Lobular, and Medullary |