Effect of Different Irrigation Solutions on Postoperative Pain and Lesion Healing

Evaluation of the Effects of Different Irrigation Solutions Used in Regenerative Endodontic Treatment of Lower Molars With Open Necrotic Apexes on Postoperative Pain and Lesion Healing

In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.

Root canal treatment is a treatment method applied to milk and permanent teeth. The inflamed and necrotic pulp where the root canal is located is cleaned, debrided chemo-mechanically, and finally filled hermetically with a biocompatible material. Necrotic immature teeth lose their restorative and defensive abilities. Since the root canal walls of these teeth are thin and weak, regenerative endodontic procedures are applied more frequently in the treatment of immature teeth to ensure root development and to restore the vitality of the pulp tissue. In this study researchers plan to conduct, three different irrigation solutions that are responsible for the release of growth factors necessary for the success of regenerative endodontic treatments will be used. These solutions; Ethylene Diamine Tetra Acetic Acid (EDTA), Etidronic Acid and Citric Acid. The aim of this study is to evaluate the effect of different irrigation solutions used in regenerative endodontic treatment of necrotic open apex molar teeth on postoperative pain. Additionally, the healing of these teeth will be monitored for 1 year.

Inclusion Criteria:• Molars with open apex

• Teeth with apical periodontitis
• Teeth for which prosthetic restoration is not planned
• Patients between the ages of 8-15 who do not have any significant health problems
• Patients who are not accompanied by periodontal problems and have good oral hygiene

Exclusion Criteria:• People with systemic disease and allergic reactions

• Severely damaged teeth
• If the tooth has previously undergone root canal treatment.
• Use of antibiotics, anti-inflammatory and painkillers in the last two weeks