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| Name | Class |
|---|---|
| Shenzhen People's Hospital | OTHER |
| Dongyuan People's Hospital | UNKNOWN |
| Kunming Children's Hospital | OTHER |
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The goal of this clinical trial is to learn how postoperative infusion of dexmedetomidine would influence postoperative delirium in elderly patients undergoing lung surgery. The main questions it aims to answer are :
Participants will undergo routine postoperative care:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experiment | Experimental |
| |
| Control | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexmedetomidine injection | Drug | Combining with 3 μg.kg-1 sufentanil, 3 μg.kg-1 dexmedetomidine is injected through intravenous patient controlled anesthesia pump in a 2 ml bolus with 20 minutes lock-out, and a background infusion rate of 2 ml per hour. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative delirium | Delirium is assessed at 8 am and 8 pm for 3 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative nausea and vomiting | Assessed twice a day for 7days after surgery | |
| incidence of postoperative complications | Other postoperative complications including including hypotension, hypertension, bradycardia, tachycardia, and hypoxemia |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Rui Zhao | Department of Anesthesiology, Kunming Children's Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kunming Children's Hospital | Kunming | Yunnan | 650100 | China |
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| ID | Term |
|---|---|
| D020927 | Dexmedetomidine |
| D017409 | Sufentanil |
| ID | Term |
|---|---|
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| Sufentanil injection | Drug | 3 μg.kg-1 sufentanil is injected through intravenous patient controlled anesthesia pump in a 2 ml bolus with 20 minutes lock-out, and a background infusion rate of 2 ml per hour. |
|
| Assessed daily for 3 days after surgery |
| Pain intensities | patient pain assessed using numeric rating scale, ranged from 0 to 11, higher score indicate higher pain intensity | Assessed daily at 8 am for 3 days after surgery |
| D005283 |
| Fentanyl |
| D010880 | Piperidines |