Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary objective of this study is to validate controlled methods of wound, including 1%w/v SLS, 3%w/v SLS, and 24-24 times tape stripping, on the forearms of subjects.
The study aims to standardize the procedures for creating wounds and systematically evaluate the effects of these methods on various skin parameters.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Moisturising Cream A | Active Comparator |
| |
| Moisturising Cream B | Active Comparator |
| |
| Test Oil | Placebo Comparator |
| |
| Untreated | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Moisturising Cream (5%) | Other | This intervention is a moisturiging cream of concentration 5% for topical application to the respective test sites. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Trans Epidermal Water Loss (TEWL) | Using the Tewameter® TM Hex | Days -02, -01, 01, 02, 05, 08, 28 |
| Skin hydration | Using the Corneometer® CM 825 | Days -02, -01, 01, 02, 05, 08, 28 |
| Skin surface topography | Assessment of skin smoothness, scaliness, roughness, wrinkles using the Visioscan® VC 20plus. | Days -02, -01, 01, 02, 05, 08, 28 |
| Measure | Description | Time Frame |
|---|---|---|
| Dermatological Assessment | Visual dermatological evaluation of the skin using the Draize scale where 0 indicates no reactions and 4 indicates severe reactions | Days -02, -01, 01, 02, 05, 08, 28 |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| NovoBliss Research Pvt Ltd | Gandhinagar | Gujarat | 382421 | India |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000074263 | Coconut Oil |
| ID | Term |
|---|---|
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
| D010938 | Plant Oils |
| D009821 |
Not provided
Not provided
Proof of science/concept
Not provided
Not provided
Not provided
Not provided
| Moisturising Cream (10%) | Other | This intervention is a moisturiging cream of concentration 10% for topical application to the respective test sites. |
|
| Coconut Oil | Other | This intervention is a 100% pure coconut oil product (Parachute Pure Coconut Oil) for topical application to the respective test sites. |
|
| Oils |