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The goal of this [type of study: Randomized control trial] is to [ see the effects of Combined Mode Kinetic Chain Exercises along with or without core stability exercises on pain, range of motion and disability ] in [ in patients with Knee Osteoarthritis].The main question it aims to answer is:
Wether core stability exercises is effective if performed along with Combined chain kinetic exercises to improves the condition of Knee Osteoarthritis? Group A will receive Core Stability Exercises along with Combined Chain Kinetic Exercises and Group B will receive combined Chain Kinetic Exercises.
Knee joint Osteoarthritis is a prevalent and multifaceted condition, affecting a substantial portion of the general population (roughly 13% of women and 10% of men 60 years). Different techniques and treatment methods have been used to treat knee osteoarthritis. In this study, I will be identifying that core stability exercise if performed along with Combined chain kinetic exercise brings benefits to the patients of knee osteoarthritis. One of the techniques is Combined Chain Kinetic Exercise that i will be applying on both groups. The other one is the set of Core stability exercises.
The research involves two intervention groups (Group A and Group B) receiving specific treatments over 60 sessions within an twelve-week period. Group A incorporates the Combined Chain Kinetic Exercise,Core stability exercises, and transcutaneous electrical nerve stimulation (TENS) with a heating pad. Group B undergoes hot packs and TENS, followed by Combined Chain Kinetic Exercise, encompassing pain levels, range of motion (ROM), and Knee Injury and Osteoarthritis Outcome Score (KOOS) scores, will be evaluated using the Numeric Pain Rating Scale, Goniometer, and KOOS. Data analysis will employ SPSS version 26. Data will be collected at baseline, immediately post-intervention, and at follow-up intervals.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Experimental | This group will include 24 participants, the interventions will be given for 35-45 mins. All the participants will follow the same standardized exercise protocol 5 days a week, for 12 weeks. |
|
| Group B | Active Comparator | This group will also include 24 participants, the interventions will be given for 20-30 mins. All the participants will follow the same standardized exercise protocol 5 days a week, for 12 weeks. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mode-Kinetic Chain Exercise With Core Stability Exercises | Other | the interventions will be given for 35-45 mins. All the participants will follow the same standardized exercise protocol 5 days a week, for 12 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Numeric pain rating scale | NPRS consists of a scale with 0-10 readings. The zero denotes no pain while 1, 2, 3 denotes to mild pain, 4, 5, 6 denotes to moderate pain while 7-10 denotes to severe pain. | 12 weeks |
| Kellgren and Lawrence system for classification of Osteoarthritis | This classification system consists of 5 grades with Grade 0 indicating normal joint and Grade 4 as maximal osteoarthritic activity in joint | 12 Weeks |
| Knee Injury and Osteoarthritic outcome score (KOOS) | The KOOS has five separate subscales: Pain, other Symptoms, Function in daily living (ADL), Function in Sport and Recreation (Sport/Rec), and knee-related Quality of Life (QOL) | 12 weeks |
| Goniometer | Active range of Motion of the patient will be assessed using a universal goniometer for knee joint flexion and extension. the data will be collected at baseline knee joint goniometry | 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Muhammad Sanaullah, MS | Riphah, Lahore 54000 | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Riphah International University | Lahore | Punjab Province | 54000 | Pakistan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41987086 | Derived | Maqsood M, Sohail J, Batool SA. Combined mode-kinetic chain exercise with and without core stability exercises on patients with knee osteoarthritis. BMC Musculoskelet Disord. 2026 Apr 15;27(1):446. doi: 10.1186/s12891-026-09531-4. |
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Assignment
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| Mode-Kinetic Chain Exercise | Other | the interventions will be given for 35-45 mins. All the participants will follow the same standardized exercise protocol 5 days a week, for 12 weeks. |
|
| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| D010146 | Pain |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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