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Part A Multiple organ dysfunction syndrome is one of the main problems in critically ill patients. Several organ dysfunctions are routinely and systematically monitored in patients admitted to intensive care units. Gastrointestinal dysfunction is currently not included in multiple organ dysfunction scores and lacks a standardised approach. At the same time, investigators earlier studies have shown that gastrointestinal dysfunction plays an essential role in the course of illness in intensive care patients. A tool for measuring dysfunction is needed to enable future studies on interventions to improve gastrointestinal function. The GIDS (GastroIntestinal Dysfunction Score) combines different clinical signs and symptoms commonly observed and documented in patients in the ICU into a scoring system, allowing distinguishing between different grades of severity of dysfunction. The investigators will only use observations documented during the patient's stay in the intensive care unit without additional measurements and calculate gastrointestinal (GIDS) and other organ dysfunction scores.
Part B Phosphate is an electrolyte commonly measured and often corrected, while the indications and clear guidance for correction are insufficiently studied. The results of this study will assist in specifying indications for the correction of phosphate levels better and refine the management strategies in the future. Only phosphate levels measured as part of routine care will be documented, no additional samples for study purposes will be taken, and the study will not influence the treatment of phosphate disorders.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Data collection | Other | Sites will recruit all consecutive adult patients admitted to ICU, to a maximum of 120 patients or a maximum recruitment period of 8 weeks, whichever comes first |
| Measure | Description | Time Frame |
|---|---|---|
| 28 day outcome | 28 day all cause mortality | 28 days after ICU admission |
| 90 day outcome | 90 day all cause mortality | 90 days after ICU admission |
| Measure | Description | Time Frame |
|---|---|---|
| ICU length of stay | ICU length of stay/days alive and free of ICU by day 28 | 28 days after admission to ICU |
| ICU length of stay | ICU length of stay/days alive and free of ICU by day 90 |
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Inclusion Criteria:
Exclusion Criteria:
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All patients admitted to the ICU within in the recruitment period will be recruited to the trial.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospitals of North Midlands NHS Trust | Stoke-on-Trent | United Kingdom |
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| 90 days after admission to ICU |
| Hospital length of stay | Hospital length of stay/days alive and free of hospital by day 28 | 28 days after admission |
| Hospital length of stay | Hospital length of stay/days alive and free of hospital by day 90 | 90 days after admission |
| Free of organ support | Days alive and free of organ support (including PN free days) by day 28 | 28 days after admission |
| ID | Term |
|---|---|
| D003625 | Data Collection |
| ID | Term |
|---|---|
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D017531 | Health Care Evaluation Mechanisms |
| D011787 | Quality of Health Care |
| D017530 | Health Care Quality, Access, and Evaluation |
| D011634 | Public Health |
| D004778 | Environment and Public Health |
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