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This study is a multi-center observational study.The start time for data collection is May 1, 2024. Patients' baseline and treatment data will be collected under informed concent. The purpose of this case registry study was to evaluate the safety and efficacy of irinotecan hydrochloride liposome injection II based therapy in Chinese patients with pancreatic cancer in the real world by collecting, understanding, and analyzing the etiology, clinical features, treatment pattern, treatment outcomes, and pharmacoeconomics changes in pancreatic cancer patients receiving this regimen.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Perioperative cohort | Irinotecan liposome II combination therapy regimen for perioperative patients |
| |
| First line cohort | Irinotecan liposome II combination therapy regimen for first line advanced patients | ||
| Second line cohort | Irinotecan liposome II combination therapy regimen for second line advanced patients | ||
| Late stage third line and above cohort | Irinotecan liposome II combination therapy regimen for third line and above advanced patients |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Irinotecan liposome II combination therapy regimen | Drug | Irinotecan liposome II combination therapy regimen |
|
| Measure | Description | Time Frame |
|---|---|---|
| rwTEAE | real word treatment emergent adverse event | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| OS | real word overall survival | 3 years |
| PFS | real word progression free survival | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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Pancreatic cancer patients in China
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Taiping Zhang, doctor | Contact | +86 13520132976 | tpingzhang@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Taiping Zhang, doctor | Peking Union Medical College Hospital, Beijing, China | Principal Investigator |
| Liwei Wang, doctor | Renji Hospital, Shanghai, China | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anhui Provincial Cancer Hospital | Recruiting | Hefei | Anhui | China |
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| ORR | real word objective response rate | 3 years |
| TTP | real word time to progression | 3 years |
| DCR | real word disease control rate | 3 years |
| Peking Union Medical College Hospital | Recruiting | Beijing | Beijing Municipality | 100730 | China |
|
| The First Affiliated Hospital of Guangxi Medical University | Recruiting | Nanning | Guangxi | China |
|
| The First Affiliated Hospital of Zhengzhou University | Recruiting | Zhengzhou | Henan | China |
|
| Peking Unicersity First Hospital | Recruiting | Beijing | China |
|
| Henan Provincial People's Hospital | Recruiting | Henan | China |
|
| Ningbo Medical Center Lihuili Hospital | Recruiting | Ningbo | China |
|
| Fudan University Shanghai Cancer Center | Recruiting | Shanghai | China |
|
| Renji,Hospital | Recruiting | Shanghai | China |
|
| Wuhan Union Hospital of China | Recruiting | Wuhan | China |
|
| ID | Term |
|---|---|
| D010190 | Pancreatic Neoplasms |
| ID | Term |
|---|---|
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004701 | Endocrine Gland Neoplasms |
| D004066 | Digestive System Diseases |
| D010182 | Pancreatic Diseases |
| D004700 | Endocrine System Diseases |
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