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This study aimed to investigate the efficiency of topical Bee Venom gel versus phonophoresis of Bee Venom gel to accelerate healing of chronic pressure ulcer
In this study, the Bee Venom gel was prepared in a gel formula. Patients with chronic pressure ulcers were enrolled randomly into two different groups. Group 1 received a topical application of Bee Venom gel, 3 times per weeks. While group 2 received phonophoresis of Bee Venom gel using low frequency ultrasound, 3 times per week. The treatment lasted for 8 consecutive weeks. The Image J Software is used to measure the wound surface area before and after treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1 | Experimental | Group 1 received topical application of Bee Venom gel, 3 times per week |
|
| group 2 | Experimental | Group 1 received phonophoresis of Bee Venom gel using low intensity ultrasound, 3 times per week |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| group 1 received topical Bee venom gel | Other | Group 1 received a topical application of Bee Venom gel, 3 times per weeks. The wound dressing changed day after day and was cleaned every time with normal saline. |
| Measure | Description | Time Frame |
|---|---|---|
| wound surface area wound surface area | ImageJ Software was used to measure the wound size | Before starting treatment and after 8 weeks of treatment |
| wound volume | wound volume was measured through the volumetric measurement method using a syringe filled with saline | Before starting treatment and after 8 weeks of treatment |
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Inclusion Criteria:
- Patients with stage II and III chronic neuropathic ulcers.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ashraf Hassan, professor | Badr University in Cairo | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Badr University in Cairo | Cairo | 11837 | Egypt |
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| ID | Term |
|---|---|
| D003668 | Pressure Ulcer |
| ID | Term |
|---|---|
| D012883 | Skin Ulcer |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| Group 2: Phonophoresis of Bee Venom gel | Other | group 2 received phonophoresis of Bee Venom gel using low frequency ultrasound, 3 times per weeks |
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