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The goal of this observational study is to evaluate the impact of deep learning image reconstruction on the image quality and diagnostic performance of double low-dose CTA. The main question it aims to answer is to explore the feasibility of deep learning image reconstruction in double low-dose CTA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard dose group | Raw data from 400 patients with conventional dose head and neck CTA, coronary CTA, and abdominal CTA were included. Filtered back-projection, iteration, and deep learning reconstruction were performed. To evaluate the impact of deep learning reconstruction on image quality and diagnostic performance in patients with conventional dose CTA. |
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| Double low dose group | Raw data from 800 patients with low tube voltage and contrast medium head and neck CTA, coronary CTA, and abdominal CTA were included. Filtered back-projection, iteration, and deep learning reconstruction were performed. To evaluate the impact of deep learning reconstruction on image quality and diagnostic performance in patients with double-low-dose CTA. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Deep learning image reconstruction | Diagnostic Test | Deep learning image reconstruction (DLIR) is a newly developed artificial intelligence noise reduction algorithm in recent years. It trains massive high-quality FBP data sets to learn to distinguish noise and signal, so as to selectively reduce noise and reconstruct high-quality images with low-quality image data. |
| Measure | Description | Time Frame |
|---|---|---|
| The specificity and sensitivity calculated through the optimal cutoff value of the receiver operating characteristic curve. | The specificity and sensitivity were calculated separately for the standard dose group and the double low-dose group using the optimal cutoff value from the receiver operating characteristic curve, for the purpose of comparing diagnostic accuracy between the two groups. | 2026.1 |
| Measure | Description | Time Frame |
|---|---|---|
| The signal-to-noise ratio calculated from image CT values and noise | The signal-to-noise ratio was calculated separately for the standard dose group and the double low-dose group using image CT values and noise, to assess the image quality between the two groups. | 2026.1 |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy or diseased adults undergoing CT vascular imaging
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Youfa M Tang, Doctor | Contact | 8613554101223 | 1525573397@qq.com | |
| Tan, Doctor | Contact | 86 159 2631 4149 | 1655118783@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Hao Tang, Doctor | Tongji Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology | Recruiting | Wuhan | Hubei | 430000 | China |
To protect the participant privacy, the relevant data is not shared until the participants' consent
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