The purpose of this study is to collect blood samples from a large number of individuals with cancer to create a database for researchers to use in future studies. Researchers may use this database to discover new ways to detect and treat cancer and other diseases. Future studies may use stored blood samples to discover how genes affect health and disease.

Inclusion Criteria:

• Are patients of participating study site clinics/clinical groups
• Are adults (aged 18 or older)
• Have an active cancer diagnosis with confirmatory pathology results indicating solid tumor and/or hematologic malignancy
• Participants may have other active diagnoses with confirmatory clinical results

Exclusion Criteria:

• Individuals who lack the capacity to provide informed consent
• Individuals known to be prisoners at time of biological specimen collection

Adults who have an active cancer diagnosis with confirmatory pathology results indicating solid tumor and/or hematologic malignancy

All future research requests will be submitted to Ovation.io and reviewed to ensure that they are consistent with the permissions described in the informed consent form by Ovation.io staff. If there is a question regarding whether or not the research request is consistent with the informed consent form and Ovation.io's biorepository policies, Ovation.io will request review and approval by an appropriate IRB.

Research teams whose study aims are in concordance with the purpose of the Ovation.io biorepository, may be granted access to specified coded datasets.In the case that a secondary research protocol requires biological specimen analysis to produce the requested dataset, Ovation.io will conduct the analysis on the relevant biological specimens stored in the biorepository and provide the results to the research team in the form of a de-identified dataset.

Biological specimens and associated data will be stored indefinitely.

All expert determinations performed under this protocol will be pursuant to a business associate agreement and conducted by an individual who has the relevant education and experience to perform a health information de-identification assessment.