Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Determination of high intracranial pressure (ICP) is necessary for the treatment of patients with raised ICP to improve long-term neurological outcomes. Ultrasonographic optic nerve sheath diameter (ONSD) measurement is a noninvasive, easily performed and cost effective technique for detecting high ICP.
ICP measurements via ventricular catheters provide CSF drainage and ICP reduction. The normal ICP value is less than 15 mmHg in adults. In the literature the correlation of ONSD and invasive ICP measurements were determined. The aim of study is to evaluate the correlation of ONSD and direct ICP measurements and to determine cut off ONSD value to detect ICP ≥15 mmHg.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Before Drainage | Experimental | Optic nerve sheath diameter and intracranial pressure will be measured before CSF drainage |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| After 5 ml CSF Drainage | Procedure | Optic Nerve Sheath Diameter and Intracranial Pressure measurements will be after 5 ml CSF drainage |
|
| Measure | Description | Time Frame |
|---|---|---|
| Intracranial Pressure-1 (ICP-1) | Measurement of intracranial pressure before cerebrospinal fluid (CSF) drainage | baseline time |
| Optic Nerve Sheath Diameter-1 (ONSD-1) | Measurement of optic nerve sheath diameter before cerebrospinal fluid drainage | baseline time |
| Measure | Description | Time Frame |
|---|---|---|
| Intracranial Pressure-2 (ICP-2) | Measurement of intracranial pressure 2 minutes after cerebrospinal fluid (CSF) drainage | 2 minutes after CSF drainage |
| Optic Nerve Sheath Diameter-2 (ONSD-2) | Measurement of optic nerve sheath diameter 2 minutes after cerebrospinal fluid drainage |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| GULSAH ORAK | Istanbul University - Cerrahpasa | Study Director |
| OZLEM KORKMAZ DÄ°LMEN | Istanbul University - Cerrahpasa | Study Chair |
| EREN FATMA AKCÄ°L | Istanbul University - Cerrahpasa | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University-Cerrahpasa | Istanbul | Fatıh | 34098 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 30019201 | Background | Robba C, Santori G, Czosnyka M, Corradi F, Bragazzi N, Padayachy L, Taccone FS, Citerio G. Optic nerve sheath diameter measured sonographically as non-invasive estimator of intracranial pressure: a systematic review and meta-analysis. Intensive Care Med. 2018 Aug;44(8):1284-1294. doi: 10.1007/s00134-018-5305-7. Epub 2018 Jul 17. | |
| 36983213 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 2 minutes after CSF drainage |
| Muller SJ, Henkes E, Gounis MJ, Felber S, Ganslandt O, Henkes H. Non-Invasive Intracranial Pressure Monitoring. J Clin Med. 2023 Mar 13;12(6):2209. doi: 10.3390/jcm12062209. |
| 32852360 | Background | Sharawat IK, Kasinathan A, Bansal A, Sahu JK, Sodhi KS, Dogra MR, Sankhyan N. Evaluation of Optic Nerve Sheath Diameter and Transcranial Doppler As Noninvasive Tools to Detect Raised Intracranial Pressure in Children. Pediatr Crit Care Med. 2020 Nov;21(11):959-965. doi: 10.1097/PCC.0000000000002523. |
| 18275454 | Background | Kimberly HH, Shah S, Marill K, Noble V. Correlation of optic nerve sheath diameter with direct measurement of intracranial pressure. Acad Emerg Med. 2008 Feb;15(2):201-4. doi: 10.1111/j.1553-2712.2007.00031.x. |
| ID | Term |
|---|---|
| D019586 | Intracranial Hypertension |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
Not provided
Not provided