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| Name | Class |
|---|---|
| Centre Hospitalier Universitaire de Liege | OTHER |
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This observational study aims to describe the incidence of episodes of disconnected consciousness (including near-death experience (NDE)) and episodes of connected consciousness in patients admitted to the resuscitation room, who survived a critical condition and who meet at least one of these criteria during their stay in the resuscitation room: (1) deep sedation, (2) intubation, (3) cardiopulmonary resuscitation, or (4) (non-drug-induced) Glasgow Coma Scale score = 3. We also investigate the potential (neuro)physiological markers and biomarkers. In order to help determine the potential risk factors of such episodes, cognitive factors such as dissociative propensity are also investigated. Unexpected visual and auditory stimuli will be displayed. In addition, we assess the evolution of memory, as well as short- and long-term consequences on quality of life, anxiety, and attitudes towards care.
Memory of patients who did not meet the above-mentioned criteria are also investigated. A group of 15 healthy participants will be invited to test the stimuli display.
Finally, (neuro)physiological parameters of a subsample of dying patients are also investigated.
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| Measure | Description | Time Frame |
|---|---|---|
| Detection of potential episodes of disconnected consciousness | near-death experience (using the Near-Death Experience Content scale); dream | upon awakening/discharge from the resuscitation room (max 21 days after the admission in the room) |
| Detection of potential episodes of connected consciousness | explicit recall of environmental/external stimuli upon awakening | upon awakening/discharge from the resuscitation room (max 21 days after the admission in the room) |
| Measure | Description | Time Frame |
|---|---|---|
| Risk factors | (neuro)physiological marker; biomarker; cognitive factor | in the resusctiation room admission |
| Quality of life assessment | The EuroQol five-dimension three-level questionnaire (EQ-5D-3L) comprises two sections. The first one is a five-question descriptive component which explores five dimensions (mobility, self-care, usual activities, pain/discomfort and anxiety/depression). Each question has three possible answers, rated from 1 to 3 (no problems, some problems and extreme problems). The second section is a visual analogue scale (EQ VAS; 0 "worst imaginable health state" to 100 "best imaginable health state") about their current health state. |
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Inclusion Criteria:
Exclusion Criteria:
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All adult patients admitted in the resuscitation room
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Charlotte Martial, PhD | Contact | +3243233612 | cmartial@uliege.be | |
| Pauline Fritz, Ms | Contact | pauline.fritz@uliege.be |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU of Liège | Recruiting | Liège | 4000 | Belgium |
Data will be anonymized and shared among collaborators upon reasonable request and agreement
Data will be shared with collaborators for the specified time allocated to each respective project. Whereas, data shared on the database will be anonymized and available indefinitely.
A written agreement between the groups (university or research teams)
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| ID | Term |
|---|---|
| D016638 | Critical Illness |
| D003643 | Death |
| D014474 | Unconsciousness |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D003244 | Consciousness Disorders |
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| at 6-month |
| Memory content and evolution assessment | The Memory Characteristics Questionnaire (MCQ). A total score can be derived summing all the 16 items (each on a 1-7 points Likert scale) and refers to as the amount of memory characteristics (i.e. higher total scores reflect greater amount of memory characteristics). | at 1-month |
| Detection of post-traumatic stress disorder (PTSD) | The Posttraumatic Stress Disorder Checklist 5 (PCL-5). Its total score can range from 0 to 80 (scores of ≥31 suggest a probable diagnosis of PTSD) | at 6-month |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |