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| Name | Class |
|---|---|
| Qena Oncology Center | OTHER_GOV |
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Retrospective observational study to evaluate c-MYC expression in non invasive and invasive mammry carcinoma
To correlate different levels of c-MYC expressions with variable clinical and pathological parameters of mammary carcinoma (such as patients' ages, tumor grading, staging, laterality, focality and nodal metastasis, co-existing in-situ components). This study will be carried out on archived formalin-fixed and paraffin embedded tissue blocks that were belonged to 70 women with breast lumps.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| non invasive mammary carcinoma | 35 cases with non invasive breast cancer with low and high nuclear grades and co existing microfoci of invasion |
| |
| invasive mammary carcinoma | 35 cases of invasive breast cancer undergone MRM and classify them according grading, staging and luminal subtypes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other | No intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| role of c-MYC in breast cancer | difference between expression of c-MYC in non invasive and invasive mammary carcinoma | 1 year |
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Inclusion Criteria:
Specimens of Modified Radical Mastectomies from breast carcinoma patients
Exclusion Criteria:
Cases with insufficient clinical data.
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women with breast lumps administered to oncology center
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| Name | Affiliation | Role |
|---|---|---|
| Afaf Alnashar, professor | Sohag University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sohag university | Sohag | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36721232 | Background | Gao FY, Li XT, Xu K, Wang RT, Guan XX. c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment. Cell Commun Signal. 2023 Jan 31;21(1):28. doi: 10.1186/s12964-023-01043-1. |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Dec 17, 2024 | |
| Reset | Jan 29, 2025 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Dec 17, 2024 | Jan 29, 2025 |
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formalin fixed, paraffin embedded tissue blocks of cases of mammary carcinoma