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The aim of this trial is to explore the real-world effectiveness and poteintial predictors of Sacituzumab Govitecan in Chinese metastatic breast cancer patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sacituzumab Govitecan | Sacituzumab Govitecan,10 mg/kg ivgtt d1, d8, q3w |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sacituzumab Govitecan | Drug | Sacituzumab Govitecan,10 mg/kg ivgtt d1, d8, q3w |
|
| Measure | Description | Time Frame |
|---|---|---|
| PFS | Progression free survival | 6 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| ORR | Overall Response Rate | 6 weeks |
| OS | Overall Survival | 6 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged over 18 years old with metastatic breast cancer included unresectable locally advanced breast cancer, de novo stage IV breast cancer, and recurrent metastatic breast cancer.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Biyun Wang, Professor | Contact | +8613701748410 | pro_wangbiyun@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Biyun Wang, Professor | Fudan University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fudan University Shanghai Cancer Center | Recruiting | Shanghai | Shanghai Municipality | 200032 | China |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| ID | Term |
|---|---|
| C000608132 | sacituzumab govitecan |
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| Number of participants with treatment-related adverse events as assessed by CTCAE v5.0 |
Safety |
| 6 weeks |
| D017437 |
| Skin and Connective Tissue Diseases |