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Despite the massive use of intracranial pressure in neuro-resuscitation, there is still no cerebral compliance evaluation index used in current practice to guide therapy.
In treatment guidelines for intracranial hypertension, patients are placed in a prone position at about 30 degrees. Several times a day, during nursing care, patients are flattened, which corresponds to a cerebral compliance test by adding a volume of cerebrospinal fluid to the cranial box.
This study aims to analyse the shape of the different components of the intracranial pressure waves (P1, P2, and P3) when the patient is flattened to determine an index to define the level of cerebral compliance.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clinical data collection | Other | Post-retrieval from the medical record | ||
| Therapeutic data collection | Other | Post-retrieval from the medical record | ||
| IntraCranial Pression (ICP) values collection | Other | Post-retrieval of ICP values from the monitor |
| Measure | Description | Time Frame |
|---|---|---|
| Intracranial pressure (mmHg) | Intracranial pressure is measured before (Raising the head by 30°) and during the flattening (Raising the head by 0°). Theses measures are done twice a day. The mean of theses values is calculated. | Year : 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between ICP (Intra Cranial Pressure) doses and cerebral compliance | Compare the ICP (Intra Cranial Pressure) dose value with the compliance index during the period before or after the flattening | Year : 1 |
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Inclusion Criteria:
Exclusion Criteria:
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Sedated patient on mechanical ventilation with continuous intracranial pressure monitoring
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| LAURENT GERGELE, MD | Contact | (0)477828593 | +33 | laurent.gergele@chu-st-etienne.fr |
| Name | Affiliation | Role |
|---|---|---|
| LAURENT GERGELE, MD | CHU DE SAINT-ETIENNE | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CENTRE HOSPITALIER Charponnay | Recruiting | Chaponnay | 69970 | France |
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| ID | Term |
|---|---|
| D002493 | Central Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
| ID | Term |
|---|---|
| D009422 | Nervous System Diseases |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |
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| CENTRE HOSPITALIER UNIVERSITAIRE Grenoble | Recruiting | Grenoble | 38000 | France |
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| HOPITAL NORD La Tronche | Recruiting | La Tronche | 38170 | France |
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| APHP | Recruiting | Paris | 75010 | France |
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| Hopital Lariboisiere - Ahph | Recruiting | Paris | 75010 | France |
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| CENTRE HOSPITALIER UNIVERSITAIRE Rennes | Recruiting | Rennes | 35000 | France |
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| CENTRE HOSPITALIER UNIVERSITAIRE Saint-Etienne | Recruiting | Saint-Etienne | 42055 | France |
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