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The purpose of this study is to compare the impact of different hemostasis methods during laparoscopic ovarian cystectomy on ovarian function and fertility in women with benign ovarian cysts.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| The absorbable hemostat | Experimental |
| |
| Electrocoagulation | Active Comparator |
| |
| Suture alone | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| the absorbable hemostat and suture | Combination Product | The hemostasis method of the experimental group is to use both the absorbable hemostat and suture. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Antral Follicle Count (AFC) | Antral follicle count (AFC) generally refers to the basic follicles in ovaries, which have not yet begun to develop. If the number of AFC is within the normal range (usually 5-10), it indicates that the ovarian reserve function is normal. If the number is low, it generally means that the ovarian reserve function is relatively low. If the number is high, it may be caused by polycystic ovary syndrome. Besides, AFC can be detected through ultrasound examination, and the number of AFC can directly reflect the ovarian reserve of each ovary. | Preoperative quantity and postoperative quantity for 1, 3, and 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Anti-Mullerian hormone (AMH) | Anti-Mullerian hormone (AMH), which can be detected through blood tests, is considered a reliable marker produced by ovarian granulosa cells. The level of AMH indirectly reflects the number of ovarian follicular pools and the joint reserve of both ovaries. In addition, the level of AMH fluctuates less throughout the menstrual cycle. Besides, AMH is almost unrelated to the menstrual cycle and is not affected by gonadotropin-releasing hormone (GnRH) agonists or oral contraceptives. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yanru Long | Contact | 86-13550169017 | 2801443341@qq.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Second University Hospital, Sichuan University | Recruiting | Chengdu | Sichuan | China |
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| electrocoagulation and suture | Combination Product | The active comparator group is to use electrocoagulation and suture simultaneously to stop bleeding. |
|
| suture | Other | The placebo comparator is to use suture alone for hemostasis. |
|
| Preoperative level and postoperative level at 1, 3, and 6 months |
| ID | Term |
|---|---|
| D013537 | Sutures |
| D004564 | Electrocoagulation |
| ID | Term |
|---|---|
| D053831 | Surgical Fixation Devices |
| D013523 | Surgical Equipment |
| D004864 | Equipment and Supplies |
| D002425 | Cautery |
| D013812 | Therapeutics |
| D055011 | Ablation Techniques |
| D013514 | Surgical Procedures, Operative |
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