Participation in a moderate-to-vigorous intensity physical activity program a part from the usual health care treatment

Following the usual health care treatment

The intervention comprises 16 weeks of group based High Intensity Interval Training (HIIT), with transition to individual community based Vigorous Intermittent Lifestyle Physical Activity (VILPA) over the next 12 weeks - for a total intervention period of 28 weeks.

World Health Organization-Disability Assessment Schedule II (WHODAS 2.0): Scale that assesses the activity limitations and participation restrictions experienced by the person. Through its 36 items, the WHODAS II allows us to obtain, both at a specific and general level, a measure of the severity and duration of the disability that results from the "health conditions" of people, also providing information on the "costs" that they generate in the individual, in the family or in society.

Screen for Cognitive Impairment in Psychiatry (SCIP-S): This scale is designed to assess cognitive deficits in psychiatric patients. It consists of 5 subtests that assess immediate and delayed verbal learning, working memory, verbal fluency and processing speed. The total score is the sum of the 5 subscales and its interpretation allows detecting the presence of cognitive deficit; a higher score corresponds to better cognitive performance.

The Brief Psychiatric Rating Scale (BPRS) is a rating scale which a clinician or researcher may use to measure psychiatric symptoms such as depression, anxiety, hallucinations, psychosis and unusual behaviour. It has 18 items. The rater enters a number for each symptom construct that ranges from 1 (not present) to 7 (extremely severe). It is scored by adding together the scores from the individual items, with higher scores indicating more severe symptoms.

Hamilton Depression Rating Scale (HAM-D): A 17-item mood rating scale. A score below 7 is considered to indicate no depressed mood, a score between 8 and 16 is considered to be moderate depression and a score above 18 indicates severe depression.

To measure physical activity and sedentary behavior, the activPAL3TM will be used. This is a miniature electronic logger designed to quantify daily free-living activities. With the activPAL3TM you can obtain a record of total sitting time, number of sitting time interruptions, sedentary bouts, standing time and activity time (light, moderate and vigorous-intensity).

PREMs (Patient Reported Experience Measures) refer to measures that assess the patient's experience of the care received. These measures are obtained directly from patients through surveys or questionnaires and are used to assess aspects such as communication with health care providers, participation in decision-making, access to health care services, overall satisfaction and other aspects of the patient experience. PROMs (Patient Reported Outcome Measures) focus on the measurement of self-reported outcomes related to their health, symptoms and quality of life. These measures are also obtained directly from patients through surveys or questionnaires and assess aspects such as pain intensity, physical functioning, emotional well-being, sleep quality and other health domains that are relevant to the patient. PROMs provide insight into the patient's perspective on the impact of a disease, treatment or intervention on their daily life and general well-being.