Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness

Diurnal Evaluation of Obstructive Sleep Apnea (OSA) Upper Airway Collapsibility and Muscle Responsiveness

In the framework of pathophysiological trait in obstructive sleep apnea (OSA) patients, a simplified method is proposed to measure upper airway (UA) collapsibility and muscle responsiveness during wakefulness.

Inclusion Criteria:

• Obstructive Sleep Apnea (OSA)
• At home-polygraphy with at least one EEG channel (PSG) reporting moderate-to severe obstructive sleep apnea (apnea-hypopnea index >14).

Exclusion Criteria:

• OSA treatment ongoing during two weeks before PSG
• Unstable cardio-respiratory disease in the 3 months before enrollment
• Subjects in O2 treatment