Inclusion Criteria:
Influenced by study design:
- Subject is 18 to 40 years of age.
- Subject weighs a minimum of 110 lbs.
- Baseline heart rate ≥ 45 bpm and ≤ 90 bpm.
- Baseline blood pressure:
- Systolic blood pressure ≤ 135 mmHg and ≥ 100 mmHg.
- Diastolic blood pressure ≤ 95 mmHg and ≥ 55 mmHg.
- Valid systolic blood pressure (SBP) auscultatory measurements for lateral difference is ≤ 15 mmHg.
- Valid diastolic blood pressure (DBP) auscultatory measurements for lateral difference is ≤ 10 mmHg.
- Hemoglobin value ≥ 11 g/dL.
- CO value ≤ 3.0% FCOHb.
- Subject is comfortable to read and communicate in English*. * This is to ensure the subject can provide informed consent (as study materials are currently available in English only) and can comply with study procedures.
Exclusion Criteria:
Influenced by device warning labels:
- Subject is pregnant or breastfeeding.
- Subject is experiencing dysrhythmia or arrhythmia.
Influenced by study design/environment:
- Subject is concurrently participating in another research study.
- Subjects not suitable for the investigation at the discretion of the clinical team including but not limited to the items below.
- Subjects who do not pass the health assessment for safe participation in the study procedures.
- Inability to insert or difficulty with inserting an intravenous line in the subject's hand or arm and/or an arterial line in the radial artery of the subject's wrist.