Clinical and Molecular Characteristics of Histiocytic Disorders

Clinical and Molecular Characteristics of Histiocytic Disorders

This study is being done to collect medical and personal histories as well as a samples of blood, other body fluid and/or tumor/disease tissue for current and future research studies on histiocytic disorders.

PRIMARY OBJECTIVES:

I. Define molecular signature and genomic landscape of histiocytic disorders. II. Correlate genomic findings with transcriptional abnormalities. III. Identify promising prognostic alterations and potential therapeutic targets.

OUTLINE: This is an observational study.

Patients complete questionnaires and undergo blood and tissue sample collection. Patients' medical records are also reviewed.

Inclusion Criteria:

• All patients diagnosed with histiocytic disorders and age ≥1 year

Exclusion Criteria:

• < 1 years age