The objective of this study was to develop an educational training App for ECMO care, and to apply a blended learning approach to improve the knowledge and skills of nurses.

In recent years, for patients with acute cardiac infarction, severe cardiac shock, and refractory acute respiratory distress syndrome, the intervention of Extracorporeal Membrane Oxygenation (ECMO) has become an adjunctive treatment for severe cardiopulmonary diseases, which can temporarily replace cardiopulmonary function, slow the deterioration of cardiopulmonary function, and buy time to assist in clinical treatment. However, the education and training of ECMO is mainly based on traditional classroom teaching, which has also been affected by COVID-2019, resulting in training process difficulties as nurses are easily restricted by time and environment.

Inclusion Criteria:

• licensed nurse practitioners working in the intensive care center of the teaching hospital and willing to participate in the study.

Exclusion Criteria:

• those who did not use smart phones.

There was a total of 97 participants in this study, with an average of 9 years of nursing experience; the shortest experience was 1 year, and the longest was 29 years, of which 35 (36%) participants were nurses with less than 5 years of experience, and 36 (37%) were nurses with more than 10 years of experience.