PET-CT Imaging Features of Meibomian Glands | NCT06324890

Studies
PET-CT Imaging Features of Meibomian Glands

NCT06324890

Sponsor

Zhongnan Hospital

Status

Unknown status

Last Update Posted

Mar 22, 2024Actual

Enrollment

100Estimated

Phase

Not provided

Conditions

MGD-Meibomian Gland Dysfunction
Positron-Emission Tomography
Dry Eye

Interventions

Not provided

Countries

China

Protocol Section

Identification Module Status Module Sponsor/Collaborators Module Oversight Module Description Module Conditions Module Design Module Arms/Interventions Module Outcomes Module Eligibility Module Contacts/Locations Module References Module IPD Sharing Statement Module

Results Section

Participant Flow Module Baseline Characteristics Module Outcome Measures Module Adverse Events Module More Info Module

Annotation Section

Annotation Module

Document Section

Large Document Module

Derived Section

Miscellaneous Info Module Condition Browse Module Intervention Browse Module

Protocol Section

Identification Module

NCT ID

Results Section

No data available

No data is available for this block.

Annotation Section

No data available

No data is available for this block.

Document Section

No data available

No data is available for this block.

Derived Section

Miscellaneous Info Module

Version Holder

Status Module

Record Verification Date

Feb 2024

Overall Recruitment Status or Expanded Access Status

Unknown status

Last Known Status

Recruiting

Delayed Posting

Not provided

Why Stopped

Not provided

Expanded Access Info

Start Date

Jan 31, 2024Actual

Primary Completion Date

Dec 31, 2024Estimated

Completion Date

Dec 31, 2024Estimated

First Submitted Date

Feb 27, 2024

First Submission Date that Met QC Criteria

Mar 21, 2024

First Posted Date

Mar 22, 2024Actual

Results Waived

Not provided

Results First Submitted Date

Not provided

Results First Submitted that Met QC Criteria

Not provided

Results First Posted Date

Not provided

Certification/Extension (aka Delayed Results) First Submitted Date

Not provided

Certification/Extension First Submitted that Passed QC Review

Not provided

Certification/Extension First Posted Date

Not provided

Last Update Submitted Date

Mar 21, 2024

Last Update Posted Date

Mar 22, 2024Actual

Oversight Module

Has Data Monitoring Committee (DMC)

Is FDA Regulated Drug

Is FDA Regulated Device

Is Unapproved Device

Not provided

Pediatric Postmarket Surveillance of a Device Product

Not provided

Product Exported from US

Not provided

FDAAA801 Violation

Not provided

Description Module

Brief Summary

Analysis the results of Dry eye analysis results and PET-CT imaging comprehensively

Detailed Description

Medical records of patients who visited the ophthalmology department between January 2021 and December 2023 and had a PET-CT examination in our hospital within one month were collected. The dry eye analysis results of all patients were collected, and the lacrimal river height, tear film rupture time and meibomian gland grade were counted. The results of PET-CT were collected and the SUV values of the tarsal gland were calculated.

Design Module

Study Type

Observational

Number of References to an Expanded Access Study

Not provided

Expanded Access Types

Not provided

Patient Registry

Target Follow-Up Duration

Not provided

Phases

Not provided

Interventional Study Design

Allocation

Not provided

Intervention Model

Biospecimen

No data available

No data is available for this block.

Enrollment

100Estimated

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Lacrimal river height	Measured by dry eye analyzer machine	Within a month of the PET imaging
Tear break-up time	Measured by dry eye analyzer machine	Within a month of the PET imaging
Tear-film lipid layer thickness	Measured by dry eye analyzer machine	Within a month of the PET imaging
Meibomian glands two-dimensional digital infrared images	Measured by dry eye analyzer machine	Within a month of the PET imaging

Secondary Outcomes

Not provided

Other Outcomes

Not provided

Eligibility Module

Eligibility Criteria

Inclusion Criteria:

Patients who visited the ophthalmology Department of Zhongnan Hospital from January 2021 to December 2023 and had a PET-CT examination in the hospital within one month

Exclusion Criteria:

Dry eye analysis was not performed
History of eye surgery or trauma
Other systemic diseases affecting the eyes

Accepts Healthy Volunteers

Yes

Sex

All

Sex/Gender Based

Not provided

Sex/Gender Description

Not provided

Minimum Age

Not provided

Maximum Age

Not provided

Standard Ages

ChildAdultOlder Adult

Study Population

Patients who visited the ophthalmology Department of Zhongnan Hospital from January 2021 to December 2023 and had a PET-CT examination in the hospital within one month

Sampling Method

Non-Probability Sample

Contacts/Locations Module

Central Contacts

Not provided

Overall Officials

Not provided

Locations

Facility	Status	City	State	ZIP	Country	Contacts
Zhongnan Hospital of Wuhan University	Recruiting	Wuhan	Hubei	430071	China

Condition Browse Module

MeSH Terms

ID	Term
D000080343	Meibomian Gland Dysfunction
D015352	Dry Eye Syndromes

Ancestor Terms

ID	Term
D005141	Eyelid Diseases
D005128	Eye Diseases
D007766	Lacrimal Apparatus Diseases

Browse Leaves

Not provided

Browse Branches

Not provided