This study is conducted in critically ill children with sepsis with a five years follow-up. We aim to investigate the impact of sepsis on long-term outcomes including growth, neurodevelopment, survival rate, quality of life.

Inclusion Criteria:

We included critically ill children with sepsis who successfully discharged from pediatric Intensive care units, age < 16 years.

We also included age, sex, illness severity matched critically ill children as control group.

Exclusion Criteria:

We excluded children with underlying diseases, cancer, hematologic malignancy.

We included critically ill children with sepsis who successfully discharged from pediatric intensive care units and age < 16 years. Age, sex, and illness severity matched critically ill children would be included as control group.

Children with underlying diseases, cancer, and hematologic malignancy would be excluded.