Immune Function of Colorectal Cancer Lymph Nodes

A Multiomics-based Study of the Immune Function of Colorectal Cancer Lymph Nodes

Lymph nodes are very important immune organs in the human body and play an important role in the physiological and pathological activities of the body, especially in anti-tumor immunity. The role of regional draining lymph nodes in the development of colorectal cancer is still unknown. In this study, the role of lymph nodes in the development of colorectal cancer was investigated through multicenter and multi-omics data.

Inclusion Criteria:

• Stage I-III colorectal cancer patients undergoing radical surgery
• Complete imaging, pathology and genetics multi-omics data available
• 18-75 years old

Exclusion Criteria:

• Patients with preoperative neoadjuvant therapy
• Patients with incomplete clinical information
• Patients with other malignant tumors
• Patients with acute infections or untreated chronic infections