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this study was conducted for evaluation of the clinical efficacy, safety, and potential side effects of platelet poor plasma gel versus nonfat injection in infraorbital rejuvenation
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| platelet poor plasma gel group | Active Comparator | in this group, plasma gel will be injected intradermally in the dark circles. |
|
| nanofat group | Active Comparator | in this group, nanofat will be injected intradermally and subcutaneously in the dark circles |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| platelet poor plasma gel | Biological | injection of platelet poor plasma gel in the dark circles around the eye to rejuvenate and improve pigmentation |
|
| Measure | Description | Time Frame |
|---|---|---|
| the degree of changes in the skin texture and homogeneity | the degree of changes in the skin texture and homogeneity was assessed using the five grades scale according to percentage of change in skin surface smoothness and color uniformity (1: much worse if deterioration >25%, 2: worse if deterioration <25%, 3: slightly improved if improvement <25%, 4: improved if improvement = 25%-50%, and 5: greatly improved if improvement >50%). | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Manousra University, Faculty of Medicine | Al Mansurah | Dakahlia Governorate | 35511 | Egypt |
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| nanofat | Biological | injection of nanofat in the dark circles around the eye to rejuvenate and improve pigmentation |
|