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While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.
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| Measure | Description | Time Frame |
|---|---|---|
| survival outcome of patients undergoing surgery for brain metastasis | overall survival of patients | From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months |
| Functional outcome of patients undergoing surgery for brain metastasis | change of preoperative and postoperative modified rankin scale | from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first |
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Inclusion Criteria:
Exclusion Criteria:
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Patients newly diagnosed with BM due to various primary cancers who underwent surgery at our institution
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jung-Shun Lee, M.D. | Contact | 886-6-2353535 | 5181 | nslee1218@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jung-Shun Lee, M.D. | National Cheng Kung Univsersity Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jung-Shun Lee | Recruiting | Tainan | None Selected | 70403 | Taiwan |
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| ID | Term |
|---|---|
| D001932 | Brain Neoplasms |
| ID | Term |
|---|---|
| D016543 | Central Nervous System Neoplasms |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| D001927 |
| Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |