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The goal of this observational study is to compare the prognostic differences between SBRT and Surgery for NSCLC patients with interlobular fissure invasion. The main questions it aims to answer are:
Main purpose:
Explore the survival differences between SBRT and surgery for NSCLC patients with interlobular pleural invasion.
Secondary purpose:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgery Group | Diagnosed as primary lung cancer by imaging/pathology, meeting the indications for surgical treatment; The clinical staging is cIB-IIIB stage (cT2-3N0M0), regardless of whether the staging is overestimated or underestimated as confirmed by pathology. | ||
| SBRT Group | Diagnosed as primary lung cancer by imaging/pathology, meeting the indications for SBRT treatment; The clinical staging is cIB-IIIB stage (cT2-3N0M0), regardless of whether the staging is overestimated or underestimated as confirmed by pathology. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Different treatments | Other | NSCLC patients receive the treatment of SBRT |
|
| Measure | Description | Time Frame |
|---|---|---|
| OS | Overall Survival | 3 years |
| PFS | Progression Free Survival | 3 years |
| MRFS | Distant Metatasis Free Survival | 3 years |
| LRFS | Local Relapse Free Survival | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| VC | Vital Capacity | 1 year |
| FVC | Forced Vital Capacity | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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Clinically diagnosed cIB-IIIB stage (cT2-3N0M0) NSCLC patients and tumor invades Interlobular pleura.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tianjin Medical University Cancer Institute and Hospital, Tianjin Key Laboratory of Cancer Prevention and Therapy | Recruiting | Tianjin | Tianjin Municipality | 300060 | China |
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| FEV1 |
Forced Expiratory Volume in one second |
| 1 year |
| DLCO | Diffusing Capacity of the lungs for carbon monoxide | 1 year |
| PFR | Pulmonary Function Report | 1 year |