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| Name | Class |
|---|---|
| University of Roma La Sapienza | OTHER |
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The presence of a thin endometrium plays an important role in enabling the best conditions for hysteroscopic surgery. Recently, for this purpose, many studies have evaluated the effect of preoperative administration of a variety of drugs. We explored the efficacy of random started 14-day administration of Nomegestrol Acetate/Estradiol, in rapid preparation of endometrium for hysteroscopic polypectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Patients with endometrial polyps undergone hysteroscopic polipectomy without endometrial preparation. | |
| Intervention | Experimental | Patients with endometrial polyps underwent hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol 2.5mg/1.5mg at any time of the menstrual cycle |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nomegestrol Acetate/Estradiol 2.5mg/1.5mg | Drug | hysteroscopic polipectomy after starting 14-day treatment with oral Nomegestrol Acetate/Estradiol 2.5mg/1.5mg at any time of the menstrual cycle |
| Measure | Description | Time Frame |
|---|---|---|
| Quality of endometrial preparation | Quality of endometrial preparation assessed visually intraoperatively by the surgeon using a visual analog scale from 0 to 5. | 14th day of treatment |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Andrea Etrusco | Palermo | 90123 | Italy | |||
| Marco Monti |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38897097 | Derived | Etrusco A, Agrifoglio V, Chiantera V, D'Amato A, Russo G, Golia D'Auge T, Giannini A, Riemma G, Pecorino B, Ferrari F, Lagana AS, Monti M. RETRACTED: The use of oral nomegestrol acetate/estradiol in rapid and random start preparation of endometrium before office hysteroscopic polypectomies: A multicenter, prospective, randomized controlled trial. Eur J Obstet Gynecol Reprod Biol. 2024 Aug;299:213-218. doi: 10.1016/j.ejogrb.2024.06.019. Epub 2024 Jun 10. |
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| ID | Term |
|---|---|
| D014591 | Uterine Diseases |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| ID | Term |
|---|---|
| C038501 | nomegestrol acetate |
| D004958 | Estradiol |
| ID | Term |
|---|---|
| D004963 | Estrenes |
| D004962 | Estranes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
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| Rome |
| 00161 |
| Italy |
| D000091662 | Genital Diseases |
| D011083 |
| Polycyclic Compounds |
| D045166 | Estradiol Congeners |
| D012739 | Gonadal Steroid Hormones |
| D042341 | Gonadal Hormones |
| D006728 | Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |