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Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infection among people who inject drugs (PWID) yet studies suggest that its use is low among this population which is particularly vulnerable to HIV infection. The criminal justice (CJ) system, at the intersection of increased risk of HIV infection and substance use, presents a unique opportunity to engage PWID in HIV prevention care that incudes PrEP. The study will characterize the facilitators and barriers to PrEP initiation, adherence and linkage to care among male PWID that are experiencing incarceration and develop the "PrEPare-for-Release" intervention to promote PrEP initiation, adherence and linkage to care upon release from incarceration into the community.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PrEPared For Release | Experimental | Intervention arm |
|
| Standard of Care | No Intervention | Control arm |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PrEPared for Release | Behavioral | A multilevel, behavioral and navigation intervention administered over two sessions to promote PrEP initiation, adherence and linkage to PrEP care in the community for incarcerated men with a history of injection drug use. |
| Measure | Description | Time Frame |
|---|---|---|
| PrEP initiation | Initiation of PrEP usage | Rapid, within 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Adherence to PrEP | Appropriate use of PrEP postinitiation | At least 30 days |
| Linkage to PrEP care in the community | Linkage to a community PrEP care provider for participants post-release from incarceration |
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Inclusion Criteria:
Exclusion Criteria:
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| Within 30 days post-incarceration |
| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
| D015229 | Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D004322 | Drainage |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D013514 | Surgical Procedures, Operative |
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