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| ID | Type | Description | Link |
|---|---|---|---|
| IRB 24.01.01 | Other Identifier | IRB |
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Calcified cerebral embolism (CCE) is a relatively rare but underdiagnosed cause of infarction. CCE diagnosis is made by CT. Radiological characteristics of CCE have been reported in small case series. The aim of this study was to describe clinical and radiological characteristics of CCE in a large number of patients, and to compare patients with different radiological CCE characteristics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with CCE | CCE patients identified between 2015 and 2023 |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| None, purely observational study | Other | None, purely observational study |
|
| Measure | Description | Time Frame |
|---|---|---|
| Calcified aortic brachiocephalic | looking for calcified aortic brachiocephalic (presence or absence) | baseline |
| cardiovascular risk | Study of cardiovascular risk factors (presence or absence) | baseline |
| history of stroke | Presence of a history of stroke (y/n) | baseline |
| Population | demographic characteristics age (years) | baseline |
| Population | demographic characteristics sexe (M/F) | baseline |
| history of surgical/endovascular cardiovascular intervention | surgical/endovascular cardiovascular intervention (y/n) | baseline |
| NIHSS | NIHSS score (Score between 1 and 4: minor stroke, Score between 5 and 15: moderate, stroke, Score between 15 and 20: severe stroke) Score > 20: severe stroke | baseline |
| calcified aortic arch | looking for calcified aortic arch (presence/absence) | baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with CEE treated with intravenous thrombolysis (IVT) between 2015 and 2020, and patients with AIT/stroke with a CCE identified on CT between deceber 2019 and april 2023.
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| Name | Affiliation | Role |
|---|---|---|
| Anissa MEGZARI | Centre Hospitalier Universitaire de Nīmes | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Nîmes | Nîmes | 30029 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39813005 | Result | Serghine Y, Laurent-Chabalier S, Thouvenot E, Parvu T, Renard D. Clinical and radiological characteristics of calcified cerebral embolism: a large case series including 242 calcified cerebral embolism. Acta Neurol Belg. 2025 Apr;125(2):463-468. doi: 10.1007/s13760-025-02719-w. Epub 2025 Jan 15. |
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| ID | Term |
|---|---|
| D002544 | Cerebral Infarction |
| ID | Term |
|---|---|
| D020520 | Brain Infarction |
| D002545 | Brain Ischemia |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
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| calcified carotid |
looking for calcified carotid (presence/absence) |
| baseline |
| atherosclerotic plaques | looking for atherosclerotic plaques (presence/absence) | baseline |
| calcified aortic valves | looking for calcified aortic valves (presence/absence) | baseline |
| calcified mitral valves | looking for calcified mitral valves (presence/absence) | baseline |
| CCE diameter | CCE diameter measurement (mm) | baseline |
| density | CCE density (uh) | baseline |
| involved cerebral artery | description of involved cerebral artery | baseline |
| D002493 |
| Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D020521 | Stroke |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D007238 | Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |