To compare the differences of clinical pathological, treatment and prognosis in the guided subgroups in colorectal cancer, the investigator enrolled all the colorectal cancer patients who underwent surgery and were hospitalized in the Xijing hospital.

Inclusion Criteria:

• 1. Pathologically confirmed colorectal adenocarcinoma, including hereditary colorectal cancer syndrome, such as Lynch syndrome and familial adenocarcinoma tumor polyposis, Peutz Jeghers syndrome, juvenile polyposis syndrome, and serrated polyposis syndrome;
• 2. Visit our center with complete medical records and pathological information;
• 3. Colorectal cancer patients diagnosed between 2013 and 2023.

Exclusion Criteria:

• 1. The patient has other colorectal malignancies other than adenocarcinoma;
• 2. Malignant tumors adjacent to organs invading the colon and rectum;
• 3. Malignant tumors from distant organs metastasize to the colon and rectum;
• 4. Benign colorectal lesions; 5. Patients with recurrent colorectal cancer.

Colorectal cancer patients mainly comes from the western areas of China, and would accept the surgical procedures. Participate would be followed up every 6 months after surgery.

The investigators aim to explore the clinical characteristics of colorectal cancer patients in the Xijing hospital.