This is an open-label, single, ascending dose study evaluating the PK and safety of methylone in healthy subjects.

Key Inclusion Criteria:

• Healthy adult male or female aged 25 to 55 inclusive
• Normal resting ECG
• Normal hematologic and hepatic function
• Normal renal function

Key Exclusion Criteria:

• Vital sign abnormalities
• Positive urine drug screen at screening and / or Day -1
• Current mental illness such as depression, anxiety disorder, schizophrenia or other psychotic disorders