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The 6-month clinical study was designed to investigate clinical efficacy on plaque and gingivitis for the stannous fluoride containing toothpaste (SNAP) compared to Colgate Cavity Protection Toothpaste after 3 and 6 months of product use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group I | Experimental | toothpaste brushing 2x daily morning & evening for 2 minutes |
|
| Group II | Active Comparator | toothpaste brushing 2x daily morning & evening for 2 minutes |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Test | Drug | test toothpaste containing 0.45% stannous fluoride |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Whole-Mouth Gingivitis Measurement | difference of reduction in gingival index | baseline, 3 months and 6 months |
| Whole-Mouth Dental Plaque Measurement | difference of reduction in plaque index | baseline, 3 months and 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Yiming Li, DDS MSD PhD | Loma Linda University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Loma Linda University School of Dentistry | Loma Linda | California | 92350 | United States |
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| ID | Term |
|---|---|
| D005891 | Gingivitis |
| D003773 | Dental Plaque |
| ID | Term |
|---|---|
| D007239 | Infections |
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
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| Control |
| Drug |
toothpaste containing 0.76% sodium monofluorophosphate |
|
| D009057 |
| Stomatognathic Diseases |
| D003741 | Dental Deposits |
| D014076 | Tooth Diseases |