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| ID | Type | Description | Link |
|---|---|---|---|
| RE2022-0000000349 | Other Grant/Funding Number | Society of Academic Emergency Medicine |
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The goal of this clinical trial is to test the effectiveness of the Serratus Anterior Plane Block in patients with rib fractures. The main questions it aims to answer are:
Participants will undergo the Serratus Anterior Plane. Researchers will compare this to usual care to see if this intervention improves pulmonary function and reduces opioid requirements for ED patients with rib fractures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | No Intervention | Usual care. No changes made or recommended to patients randomized to the control arm. | |
| Intervention arm (Undergoes SAPB) | Experimental | Patients randomized to this arm will receive the Serratus Anterior Plane block. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Serratus Anterior Plane Block | Procedure | Patients who undergo randomization to the intervention arm will undergo the Serratus Anterior Plane Block. |
|
| Measure | Description | Time Frame |
|---|---|---|
| PIC Score | Determine if the SAPB results in an improved pain, incentive spirometry, and cough ability (PIC) score when compared to usual care over the first five hours. The PIC score is a scoring system that can be measured serially in patients with rib fractures to assess pulmonary function and to prognosticate clinical outcomes. | 5 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Total oral morphine equivalents over the first 24 hours | Evaluate if UG-SAPB results in fewer opioid medications administered when compared to usual care over the first 24 hours. | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rhode Island Hospital | Providence | Rhode Island | 02903 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33304071 | Background | Paul S, Bhoi SK, Sinha TP, Kumar G. Ultrasound-Guided Serratus Anterior Plane Block for Rib Fracture-Associated Pain Management in Emergency Department. J Emerg Trauma Shock. 2020 Jul-Sep;13(3):208-212. doi: 10.4103/JETS.JETS_155_19. Epub 2020 Sep 18. | |
| 35106815 | Background | Kring RM, Mackenzie DC, Wilson CN, Rappold JF, Strout TD, Croft PE. Ultrasound-Guided Serratus Anterior Plane Block (SAPB) Improves Pain Control in Patients With Rib Fractures. J Ultrasound Med. 2022 Nov;41(11):2695-2701. doi: 10.1002/jum.15953. Epub 2022 Feb 2. |
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Undecided at this point as to where and how IPD will be shared for this pilot study.
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| ID | Term |
|---|---|
| D012253 | Rib Fractures |
| D059787 | Acute Pain |
| ID | Term |
|---|---|
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D013898 | Thoracic Injuries |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D000077212 | Ropivacaine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
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Research Assistants who collect the data will be blinded to which arm of the study the participants are in.
| Ropivacaine injection | Drug | For the Serratus Anterior Plane Block, Ropivacaine will be used as the anesthetic. |
|
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| 32064417 | Background | Lin J, Hoffman T, Badashova K, Motov S, Haines L. Serratus Anterior Plane Block in the Emergency Department: A Case Series. Clin Pract Cases Emerg Med. 2020 Jan 21;4(1):21-25. doi: 10.5811/cpcem.2019.11.44946. eCollection 2020 Feb. |
| 30020155 | Background | Thiruvenkatarajan V, Cruz Eng H, Adhikary SD. An update on regional analgesia for rib fractures. Curr Opin Anaesthesiol. 2018 Oct;31(5):601-607. doi: 10.1097/ACO.0000000000000637. |
| 34059325 | Background | Sarode AL, Ho VP, Pieracci FM, Moorman ML, Towe CW. The financial burden of rib fractures: National estimates 2007 to 2016. Injury. 2021 Aug;52(8):2180-2187. doi: 10.1016/j.injury.2021.05.027. Epub 2021 May 19. |
| 42159402 | Derived | Perice L, Azzo C, Cowan M, Kheirbek T, Driver L, Tokarz S, Gallegos H, Kharel R, Jarabana SG, Baird J, Pare JR. Serratus Anterior Plane Block for Acute Rib Fractures in the Emergency Department: A Randomized Controlled Trial. Acad Emerg Med. 2026 May;33(5):e70338. doi: 10.1111/acem.70338. |
| D009461 |
| Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000588 |
| Amines |