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The goal of this study is to compared efficacy of oral fluid and intravenous fluid after primary unilateral total knee arthroplasty.
The main question it aims to answer is:
Does oral fluid replacement after primary unilateral total knee arthroplasty provide a patient recover faster than intravenous fluids replacement?
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Oral fluid | Experimental |
|
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| IV fluid | Active Comparator |
|
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Oral fluid | Dietary Supplement | Postoperation
|
|
| Measure | Description | Time Frame |
|---|---|---|
| Time to stand and walk | Stand and walk with walker | Postoperative day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Time up and go | Record time since stand up and walk 3 meters, or 10 feet away, on the floor | 24 and 48 hours |
| Incidence of oliguria | Urine output < 0.5ml/kg/hr |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yot Tanariyakul, M.D. | Contact | 663930257 | y.tanariyakul@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Thammasat University | Recruiting | Khlong Luang | Changwat Pathum Thani | 12120 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32037213 | Background | Jennings JM, Mejia M, Williams MA, Johnson RM, Yang CC, Dennis DA. The James A. Rand Young Investigator's Award: Traditional Intravenous Fluid vs. Oral Fluid Administration in Primary Total Knee Arthroplasty: A Randomized Trial. J Arthroplasty. 2020 Jun;35(6S):S3-S9. doi: 10.1016/j.arth.2020.01.029. Epub 2020 Jan 22. |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| ID | Term |
|---|---|
| D005440 | Fluid Therapy |
| ID | Term |
|---|---|
| D004358 | Drug Therapy |
| D013812 | Therapeutics |
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| IV fluid | Dietary Supplement | Postoperation
|
|
| Postoperative day 1,2 |
| Incidence of nausea/vomiting | record symptom of nausea and vomiting | Postoperative day 1,2 |
| Urine specific gravity | Urine specific gravity every 4 hours | Postoperative day 1 |
| the levels of certain electrolytes | Blood chemistry | Postoperative day 1,2 |
| the levels of creatinine | Blood chemistry | Postoperative day 1,2 |
| the levels of blood urea nitrogen (BUN). | Blood chemistry | Postoperative day 1,2 |
| Complications | Pulmonary edema, heart failure, acute kidney injury | Until postoperative 3months |
| D012216 |
| Rheumatic Diseases |