The goal of this observational study is to comparison of the complications in multiple myeloma patients who received autologous stem cell transplantation between in HEPA-filtered room and non-HEPA-filtered room. The main questions it aims to answer are:

• The incidence of febrile neutropenia, infection, and duration of hospital stay
• 2-year progression free survival Participants will be collected the data of baseline diagnosis, treatment, treatment results and complications during admission and follow-up visits from hospital medical record.

Inclusion Criteria:

• aged 18 - 65 years old
• Patients with multiple myeloma undergoing treatment with autologous stem cell transplantation and having a Hematopoietic Cell Transplantation-Specific Comorbidity Index (HCT-CI) score less than or equal to 2
• Patients must provide signed consent to participate in the research if they undergo ASCT after the study has been approved.
• If patients undergo ASCT before the study approval, retrospective data will be collected.

Exclusion Criteria:

• Patients with concomitant other types of cancer
• Patients who refuse to participate in the study.

multiple myeloma patients who received autologous stem cell transplantation

Need a consensus from colleagues