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| ID | Type | Description | Link |
|---|---|---|---|
| 2P60AA007611-403343 | Other Grant/Funding Number | National Institute on Alcohol Abuse and Alcoholism | |
| 2P60AA007611 | U.S. NIH Grant/Contract | View source |
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The goal of this clinical trial is to test the prosocial effects of personally-relevant, high-intensity episodic future-thinking (EFT) cues in alcohol use disorder persons and related brain mechanisms. The main question[s] this trial aims to answer are:
Researchers will compare the experimental (high-intensity group) and control (low-intensity) groups to see if there are differences in the results for the questions outlined above.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High-Intensity | Experimental | Participants will receive high-intensity episodic future-thinking cue images, and high-intensity episodic recent-thinking cue images during an MRI decision-making task. |
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| Low-Intensity (Control) | Active Comparator | Participants will receive low-intensity episodic future-thinking cue images, and low-intensity episodic recent-thinking cue images during an MRI decision-making task. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High-Intensity Cue | Behavioral | Participants in the high-intensity group will receive high-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future. |
| Measure | Description | Time Frame |
|---|---|---|
| Increase Prospective Thinking | High-intensity episodic future-thinking image cues will change prospective thinking. | Study Day Visit (Day 1) |
| Delayed Rewards | High-intensity episodic future-thinking image cues will change preference for delayed rewards, which will be measured using a behavioral delayed discounting task. | Study Day Visit (Day 1) |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Indiana University School of Medicine - Goodman Hall | Recruiting | Indianapolis | Indiana | 46202 | United States |
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| ID | Term |
|---|---|
| D000437 | Alcoholism |
| ID | Term |
|---|---|
| D019973 | Alcohol-Related Disorders |
| D019966 | Substance-Related Disorders |
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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Eligible participants will be randomly assigned to either the high-intensity (experimental) or low-intensity (control) groups.
| Low-Intensity Cue | Behavioral | Participants in the low-intensity group will receive low-intensity image cues that represent self-reported events they did on the previous day and self-reported events they look forward to in the future. |
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