Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to evaluate the incidence and severity of retinopathy and opticopathy one year after treatment with hypofractionated stereotactic photon radiotherapy due to uveal melanoma. Patients will be imaged before radiation, as well as 3, 6, 9 and 12 months after radiation using sonography funds photography, optical coherence tomography angiography, oximeter and microperimetry.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Uveal Melanoma | Patients with newly diagnosed uveal melanoma, which will be treated with hypofractionated stereotactic photon radiotherapy as clinical routine. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Clinical examination and multimodal ocular imaging | Diagnostic Test | Imaging consists of sonography, fundus photography, oximeter, optical coherence tomography angiography, and Microperimetry. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence and Severity of Retinopathy | Incidence and severity of retinopathy will be evaluated as non-perfusion areas on optical coherence tomography angiography | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence and Severity of Opticopathy | Incidence and severity of retinopathy will be evaluated on clinical examination and fundus photography | 1 year |
| Functional Outcome | Functional outcome will be evaluated as mean retinal sensitivity. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Patients with newly diagnosed uveal melanoma, who will be treated with hypofractionated stereotactic photon radiotherapy as part of clinical routine, will be included in the study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Judith Kreminger, MD | Contact | 0043 1 40400 48470 | judith.kreminger@meduniwien.ac.at | |
| Reinhard Told, MD, PhD | Contact | 0043 1 40400 48470 | reinhard.told@meduniwien.ac.at |
| Name | Affiliation | Role |
|---|---|---|
| Reinhard Told, MD, PhD | Department for Ophthalmology and Optometry, Medical University of Vienna | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Ophthalmology and Optometry, Medical University Vienna | Recruiting | Vienna | 1090 | Austria |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D000098943 | Uveal Melanoma |
| ID | Term |
|---|---|
| D008545 | Melanoma |
| D018358 | Neuroendocrine Tumors |
| D017599 | Neuroectodermal Tumors |
| D009373 | Neoplasms, Germ Cell and Embryonal |
Not provided
Not provided
| ID | Term |
|---|---|
| D010808 | Physical Examination |
| ID | Term |
|---|---|
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
Not provided
Not provided
Not provided
Not provided
Not provided
| 1 year |
| Incidence and Severity of Retinopathy and Opticopathy in oximeter | Incidence and severity of retinopathy and opticopathy will be evaluated using oxygen saturation | 1 year |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D009380 | Neoplasms, Nerve Tissue |
| D018326 | Nevi and Melanomas |
| D014604 | Uveal Neoplasms |
| D005134 | Eye Neoplasms |
| D009371 | Neoplasms by Site |
| D005128 | Eye Diseases |
| D014603 | Uveal Diseases |