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This study aims to examine the effectiveness of Adaptogen Elixir herbal drink in relieving emotions and improving sleep quality. Participants will be randomly assigned to either the placebo group or the Adaptogen Elixir herbal drink group, with 25 participants in each group. On the day of the experiment (week 0), participants are required to collect blood and saliva samples, fill out questionnaires assessing sleep disorders and stress condition, and use a sleep monitoring system to track their sleep and autonomic nervous system conditions. Subsequently, participants will be given the experimental samples and instructed to consume them continuously for 4 weeks following the instruction. Follow-up assessments will be conducted in the 2nd and 4th weeks, participants are required to collect blood and saliva samples, fill out questionnaires assessing sleep disorders and stress condition, and use a sleep monitoring system to track their sleep and autonomic nervous system conditions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo drink | Placebo Comparator | consume 1 drink per day for 4 weeks |
|
| Adaptogen Elixir drink | Experimental | consume 1 drink per day for 4 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo drink | Dietary Supplement | consume 1 drink per day for 4 weeks |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Sleep monitoring | The difference of electrocardiosignal between two specific points on the body surface will be used to reflect sleep state. | Week 0 (Baseline), Week 2, Week 4 |
| Sleeping qualityy | The Pittsburgh Sleep Quality Index (PSQI) will be utilized to assess sleeping quality. The minimum value is 0, the maximum value is 42. The higher the score, the worse the outcome. | Week 0 (Baseline), Week 2, Week 4 |
| Sleeping disorders | Insomnia Severity Index (ISI) will be utilized to assess sleeping disorders. The minimum value is 0, the maximum value is 28. The higher the score, the worse the outcome. | Week 0 (Baseline), Week 2, Week 4 |
| Measure | Description | Time Frame |
|---|---|---|
| Neuropeptide Y concentration | Venous blood samples will be collected to measure concentrations of Neuropeptide Y. | Week 0 (Baseline), Week 2, Week 4 |
| Cortisol concentration | Saliva samples will be collected to measure concentrations of cortisol. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hsin-Chien Lee, Doctor | Taipei Medical University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Taipei Medical University | Taipei | Taiwan |
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| ID | Term |
|---|---|
| D012893 | Sleep Wake Disorders |
| D001008 | Anxiety Disorders |
| ID | Term |
|---|---|
| D009422 | Nervous System Diseases |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Adaptogen Elixir drink |
| Dietary Supplement |
consume 1 drink per day for 4 weeks |
|
|
| Week 0 (Baseline), Week 2, Week 4 |
| Anxiety | Generalized Anxiety Disorder-7 (GAD-7) will be utilized to assess anxiety. The minimum value is 0, the maximum value is 21. The higher the score, the worse the outcome. | Week 0 (Baseline), Week 2, Week 4 |
| Low Frequency/High Frequence (LF/HF) ratio | A sleep monitoring system will be utilized to measure LF/HF ratio | Week 0 (Baseline), Week 2, Week 4 |
| D001523 | Mental Disorders |