Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism

To Compare the Effectiveness of Vitamin D & Levothyroxine Combination Therapy and Levothyroxine Alone on Serum Lipid Profile in Patients With Hypothyroidism

The goal of this clinical trial is to study the improvement of lipid levels in hypothyroid individuals after staring treatment.

The main question it aims to answer is:

• whether adding Vitamin D to standard therapy has any additional benefits

Participants will be given Vitamin D in replacement doses according to their pre-existing Vitamin D level in addition to levothyroxine.

Researchers will compare them with another group receiving only levothyroxine to see how much lipids improve in them

Inclusion Criteria:

• Patients of all genders.
• Age more than 12 years
• Biochemically hypothyroid (overt & subclinical)
• Vitamin D level between 10-70ng/ml
• TC <250mg/dl, LDL 70-144mg/dl, TGs 150-499mg/dl

Exclusion Criteria:

• Known Atherosclerotic Cardiovascular Disease
• BMI>35kg/m2
• History of Alcoholism (>14 units/day)
• History of Beta blocker intake
• Patient taking lipid lowering drugs