Preliminary Exploration of Thromboelastography in the Monitoring of Anticoagulation in Maintenance Hemodialysis Patients

Preliminary Exploration of Thromboelastography in the Monitoring of Anticoagulation in Maintenance Hemodialysis Patients

Objectives: To investigate the role of thromboelastography parameters (R, K, Angle, MA) in monitoring anticoagulation in maintenance hemodialysis (MHD) patients.

Subjects: Two hundred stable MHD patients. Methods: An observational study. Primary outcome: Relationship between thromboelastography parameter R Value and coagulation of hemodialysis circuit and dialyzer.

Secondary outcome: Relationship between thromboelastography parameters (K Value, Angle and MA) and coagulation of hemodialysis circuit and dialyzer.

Inclusion Criteria:

1. male or female patients aged over 18 years
2. stable patients undergoing maintenance hemodialysis treatment for at least 3 months
3. signed informed consent form

Exclusion Criteria:

1. concomitant with severe diseases such as active malignancy, severe liver diseases, systemic infection, etc.
2. planned or ongoing pregnancy or lactation
3. unsuitable for inclusion in this study after assessment