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During their first year of life, children spend more than half their time sleeping, a function essential to their neurodevelopment. This period of maturation and development of the future adult is considered extremely vulnerable to environmental exposure. During this period, the child's diet is mainly provided by breastfeeding, where persistent chemical substances have been found. A cocktail of 19 mostly persistent substances (POPs) present in breast milk has recently been identified as the main contributor to neurodevelopmental risk. However, the reality of their impact on neurophysiological development, in particular on infant sleep, has yet to be assessed.
In this project, the sleep of children under 6 months of age will be studied using an actimetry watch worn for 7 days by the child, accompanied by a sleep diary. Exposure to environmental pollutants will be assessed by measuring their presence in the infant's milk (breastfeeding) and wearing a silicone bracelet to collect air pollutants. A questionnaire on exposure will complement this evaluation.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| New born | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 7-day actimetry sleep recording | Device | 7-day actimetry sleep recording |
| |
| Measure | Description | Time Frame |
|---|---|---|
| total sleep time per day in infants using actimetry | total sleep time per day (min)) in infants using actimetry | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Concentration of various substances in breast milk | 1 day | |
| concentration of chemical polluants on newborn bracelets | 1 day | |
| Child Temperature level (°C) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Karen CHARDON, Pr | Contact | (33) 03.22.82.78. 65 | Karen.chardon@u-picardie.fr | |
| Elodie HARAUX, Pr | Contact | (33) 03.22.08.75.60 | Haraux.elodie@chu-amiens.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU Amiens | Recruiting | Amiens | 80054 | France |
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| Determination of environmental pollutants in breast milk |
| Other |
Determination of environmental pollutants in breast milk |
|
| Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child | Other | Measurements of environmental pollutants in indoor air deposited on the bracelet worn by the child |
|
| Continuous recording of the child's temperature for 7 days | Other | Continuous recording of the child's temperature for 7 days |
|
| Use of a sleep diary for 7 days | Other | Use of a sleep diary for 7 days |
|
| Parental questionnaire of environmental exposure | Other | Parental questionnaire of environmental exposure |
|
| 7 days |
| ID | Term |
|---|---|
| D008895 | Milk, Human |
| ID | Term |
|---|---|
| D008892 | Milk |
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
| D005502 | Food |
| D019602 | Food and Beverages |
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