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The purpose of this study is to assess wether the SONDA visual field test is suitable for patients with a supra sellar tumour.
The objective of this study is to determine whether SONDA is non-inferior in predicting visual field limitations compared to the SAP in patients with a (supra)sellar tumor. The study population will be made up of patients with a (supra)sellar tumor complicated by compression of the optic chiasm as well as healthy controls. The patients will be asked to join the study when the patients are referred to the UMCG for further diagnostics and treatment. In case the patients show signs of visual field loss the patients will be asked to participate in the study. The researchers will reuse data from healthy controls collected in previous studies where possible and, if necessary for age matching, recruit new participants. Participants will be asked to perform the SONDA test before and after surgery. The first time the participants will perform the test twice and will also perform routine eye test and be asked to fill in a questionnaire to evaluate the experience.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients | Participants will undergo a visual acuity test. Next they will perform the SONDA test 2 times at one visit and once more in a later visit Participants will fill in a questionnaire |
| |
| Healthy controls | Participants will perform the SONDA test 2 times |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SONDA | Diagnostic Test | Perimetry based visualfield analysis |
|
| Measure | Description | Time Frame |
|---|---|---|
| Convert validity | Difference (dB) between the predicted MD (SONDA) and the assessed MD (SAP), expressed as delta MD. | Baseline |
| Test-retest reliability | The variability of the predicted MD (dB) between consecutive measurements in the same person. | baseline 1, baseline 2, 6-8 weeks post-operative |
| Measure | Description | Time Frame |
|---|---|---|
| Experience | The experience of patients expressed in scores and descriptives based on a questionnaire: Questionnaire Standardized Oculomotor and Neuro-Ophthalmic Disorder Assessment | Baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with a (supra)sellar tumour and healthy controls
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jos MA Kuijlen, MD/PHD | Contact | 050 361 2837 | jmakuijlen@umcg.nl |
| Name | Affiliation | Role |
|---|---|---|
| Jos MA Kuijlen, MD/PHD | University Medical Center Groningen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UMCG | Groningen | Provincie Groningen | 9713 GZ | Netherlands |
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| ID | Term |
|---|---|
| D010911 | Pituitary Neoplasms |
| D006423 | Hemianopsia |
| ID | Term |
|---|---|
| D004701 | Endocrine Gland Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D007029 | Hypothalamic Neoplasms |
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| D015173 |
| Supratentorial Neoplasms |
| D001932 | Brain Neoplasms |
| D016543 | Central Nervous System Neoplasms |
| D009423 | Nervous System Neoplasms |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D007027 | Hypothalamic Diseases |
| D010900 | Pituitary Diseases |
| D004700 | Endocrine System Diseases |
| D014786 | Vision Disorders |
| D012678 | Sensation Disorders |
| D009461 | Neurologic Manifestations |
| D001766 | Blindness |
| D005128 | Eye Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |