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| Name | Class |
|---|---|
| Beijing Chao Yang Hospital | OTHER |
| Beijing Friendship Hospital | OTHER |
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The objective of this retrospective, prospective, multicenter cohort study is to determine the risk factors for deterioration of CVT patients after admission and establish a scoring model for risk stratification of patients. This study included two stages, the first stage was to enroll CVT patients from a single center from 2017 to 2022 for modeling, and the second stage was to enroll CVT patients from three centers in 2023 for external validation
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| Measure | Description | Time Frame |
|---|---|---|
| Number of Participants with CVT deteriorated on radiology | One of the following situations occurs: new or progressive bleeding or infarction, midline displacement (>3mm), increased cerebral edema, and placeholder effect by comparing the CT before and after; mRS and/or GCS decreased due to decreased consciousness, increased focal neurological impairment, new focal neurological impairment or death. | After admission until discharge, a maximum of 30 days |
| Number of Participants with altered neurological function | mRS Score decreased due to decreased consciousness, increased focal neurological impairment, new focal neurological impairment or death. | After admission until discharge, a maximum of 30 days |
| Number of Participants with altered consciousness | GCS Score decreased | After admission until discharge, a maximum of 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Neurological function at 30th day after onset (mRS) | MRS was used to evaluate the neurological function of patients at 30th day after onset. | 30th day after onset |
| Emergency surgery rates | Rate of patients receiving emergency surgery for severe brain edema or hernia (including endovascular treatment and bone flap decompression). |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with cerebral venous thrombosis (CVT)
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Capital Medical University Affiliated Beijing Tiantan Hospital | Beijing | Beijing Municipality | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39815140 | Derived | Feng Y, Mo S, Li X, Jiang P, Wu J, Li J, Liu P, Wang S, Liu Q, Tong X. Development and validation of a score for clinical deterioration in patients with cerebral venous thrombosis. Neurosurg Rev. 2025 Jan 16;48(1):56. doi: 10.1007/s10143-025-03224-7. |
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| ID | Term |
|---|---|
| D020767 | Intracranial Thrombosis |
| ID | Term |
|---|---|
| D002542 | Intracranial Embolism and Thrombosis |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| After admission until discharge, a maximum of 30 days |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D013923 | Thromboembolism |
| D016769 | Embolism and Thrombosis |