The purpose of this study is to assess the sensation of ocular dry eye symptom after an intravitreal injection of anti-VEGF.

The recrutement of the patient is done during the inclusion of the patient by the nurses of the ophtalmological service of clermont-ferrand and confirm by an ophtalmologist of the service.

A mesure of the OSDI is done before the injection, then at 1 day, on week by a phone call. Each of this mesures are done for the 2 other injections.

Before each of this injection, a clinical mesure is done by a lacrydiag: the atrophy of the meibomian glands, the non-invasive break-up time, interferometry, the heigh of the tear meniscum.

Inclusion Criteria:

• Patient with exsudative age-related macular degeneration, diabetic macular edema or retinal vein occlusion
• Patient with 3 ocular intravitreal injections of anti-VEGF in one eye

Exclusion Criteria:

• pregnant or breastfeeding woman
• intravitreal injection before the study
• intravitreal injection in both eyes
• allergy of betadine
• guardianship patient

patient with retinal injury who will have 3 injections as the induction protocol (1 injection per month) for one eye and that didn't had any injection before.