Effects of High-intensity Interval Training on Myocardial Strain in Metabolic Syndrome Patients

Effects of High-intensity Interval Training on Myocardial Strain in Patients With Metabolic Syndrome

the effects of high-intensity interval training on myocardial function will be studied in a group of patients under medical treatment for the components of metabolic syndrome.

Objective: To analyze the effects of high-intensity interval training (HIIT) on myocardial function of metabolic syndrome patients.

Methods and design. Randomized clinical trial with a control group. Project was developed in association with the regional general hospital. Pre and post-intervention evaluation after 16 weeks of training for the HIIT group.

Subjects: Recruited using adverts published on public medical center boards. Up to 30 subjects per group (HIIT and CONTROL) will be recruited (at least 20% women) Measurements. Echocardiography: Global longitudinal strain (GLS), Mitral filling parameters, myocardial dimensions, and myocardial wall thickness.

Cardiorespiratory fitness: Maximal oxygen consumption, Maximal power output, Maximal oxygen pulse.

Clinical: Metabolic syndrome components and derived variables (e.g., triglycerides/high-density lipoprotein ratio) Body composition by anthropometric measurements and dual-energy X-ray absorptiometry.

Inclusion Criteria:

• Clinical diagnosis of metabolic syndrome.
• Capacity to exercise on a stationary bike
• Inhabitant of the province of Toledo

Exclusion Criteria:

• Untreated cardiovascular disease with hemodynamic instability
• Untreated respiratory disease, symptomatic.
• Untreated metabolic disease.
• Untreated renal disease requiring dialysis.
• Contraindications for high-intensity exercise training