Spondyloarthritis (SpA) is a group of chronic inflammatory pathologies whose progression over time is poorly defined, and in particular the clinical and instrumental elements that can predispose to a condition of disease severity are not completely known. It would be important to have an idea of what the predisposing factors are, possibly already at baseline, and possibly also at follow up, of severe disease, so as to be able to act early with more aggressive and targeted therapies on these patients, so as to achieve remission.

Inclusion Criteria:

• age >18 years;
• Diagnosis of SpA confirmed by the rheumatologist with duration of symptoms <
• 2 years;
• Signature of the written informed consent to the study

Exclusion Criteria:

• Age < 18 years;
• Patients suffering from other rheumatic pathologies (even in overlap), or genetic diseases such as Marfan syndrome, Ehlers Danlos syndrome
• Any medical or psychiatric condition that in the judgment of the investigator would prevent the participant from complying with the protocol or completing the study according to the protocol.
• Refusal to sign the informed consent to the study.

patients with recent onset of SpA (duration of symptoms ≤2 years) and diagnosis made by the rheumatologist.